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LTK

Anti-LTK Recombinant Antibody Products

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For Research Use Only. Not For Clinical Use.


The protein encoded by this gene is a member of the ros/insulin receptor family of tyrosine kinases. Tyrosine-specific phosphorylation of proteins is a key to the control of diverse pathways leading to cell growth and differentiation.
Protein class

Disease related genes, Enzymes, Metabolic proteins, Potential drug targets

Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Cell type enhanced (Distal enterocytes, Gastric mucus-secreting cells, Proximal enterocytes, Hepatic stellate cells, Intestinal goblet cells)

Immune cell specificity

Group enriched (MAIT T-cell, plasmacytoid DC)

Cell line specificity

Cell line enhanced (HEL, NB-4, RH-30, THP-1)

Interaction

Homodimer; homodimerizes following ligand-binding (PubMed:34646012). Part of a complex including LTK, TNK2 and GRB2, in which GRB2 promotes LTK recruitment by TNK2 (PubMed:19815557).

Molecular function

Kinase, Receptor, Transferase, Tyrosine-protein kinase

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