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LTK
The protein encoded by this gene is a member of the ros/insulin receptor family of tyrosine kinases. Tyrosine-specific phosphorylation of proteins is a key to the control of diverse pathways leading to cell growth and differentiation.
Protein class
Disease related genes, Enzymes, Metabolic proteins, Potential drug targets
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (Distal enterocytes, Gastric mucus-secreting cells, Proximal enterocytes, Hepatic stellate cells, Intestinal goblet cells)
Immune cell specificity
Group enriched (MAIT T-cell, plasmacytoid DC)
Cell line specificity
Cell line enhanced (HEL, NB-4, RH-30, THP-1)
Interaction
Homodimer; homodimerizes following ligand-binding (PubMed:34646012). Part of a complex including LTK, TNK2 and GRB2, in which GRB2 promotes LTK recruitment by TNK2 (PubMed:19815557).
Molecular function
Kinase, Receptor, Transferase, Tyrosine-protein kinase
More Types Infomation
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: WB, IHC
- Rabbit Anti-LTK Recombinant Antibody (clone R02-8A4) (VS3-FY2025)
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- Species Reactivity: Human, Rat
- Type: Rabbit IgG
- Application: WB, IHC-P
- Mouse Anti-LTK Recombinant Antibody (VS-0823-LC1) (VS-0823-LC1)
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- Species Reactivity: Human, Mouse, Rat
- Type: Mouse IgG1, kappa
- Application: WB, IP, IF, ELISA
- Anti-Human LTK Recombinant Antibody Fab Fragment (FAM150B) (TAB-0712CL-F(E))
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- Type: Human antibody
- Application: ELISA, FC
- Anti-Human LTK Recombinant Antibody Fab Fragment (FAM150A) (TAB-0711CL-F(E))
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- Type: Human antibody
- Application: ELISA, FC
- Anti-Human LTK Recombinant Antibody scFv Fragment (FAM150B) (TAB-0712CL-S(P))
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- Type: Human antibody
- Application: ELISA, FC
- Anti-Human LTK Recombinant Antibody scFv Fragment (FAM150A) (TAB-0711CL-S(P))
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- Type: Human antibody
- Application: ELISA, FC
- Human Anti-LTK Antibody, mRNA (TAB-505CL-mRNA)
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- Species Reactivity: Human
- Anti-Human LTK Recombinant Antibody (FAM150B) (TAB-0712CL)
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- Type: Human antibody
- Application: ELISA, FuncS, FC, WB, Activ, IP, IHC
- Anti-Human LTK Recombinant Antibody (FAM150A) (TAB-0711CL)
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- Type: Human antibody
- Application: ELISA, FuncS, FC, WB, Activ, IP, SPR, IHC
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- Species Reactivity: Human
- Type: ADCC enhanced antibody
- Anti-Human LTK Recombinant Antibody (TAB-505CL)
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- Species Reactivity: Human
- Type: Antibody
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For Research Use Only. Not For Clinical Use.