Rabbit Anti-LTK Recombinant Antibody (clone R02-8A4) (CAT#: VS3-FY2025)
The R02-8A4 recombinant monoclonal antibody is able to identify human LTK. It cross-reacts with rat. It is suitable for use in a variety of assays, including WB, IHC-P. This LTK antibody is guaranteed for western blot analysis of LTK in A549, HL-60, U2OS, C6 lysates and immunohistochemistry analysis of paraffin-embedded human lung cancer.
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WB
Figure 1 Anti-LTK Antibody (VS3-FY2025) in WB.
The LTK expression in A549, HL-60, U2OS, C6 lysates were detected using the anti-LTK by western blot assay.
IHC
Figure 2 Anti-LTK Antibody (VS3-FY2025) in IHC.
Immunohistochemistry staining of paraffin-embedded human lung cancer using the anti-LTK antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
Specifications
- Immunogen
- Synthetic peptide of human LTK
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human and Rat LTK
- Species Reactivity
- Human, Rat
- Clone
- R02-8A4
- Applications
- Western Blot, Immunohistochemistry-Paraffin
- MW
- The calculated weight of the target protein is approximately 92 kDa, while the observed molecular weight stands at 92 kDa.
- Related Disease
- Human lung cancer
Product Property
- Purification
- Affinity Purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% glycerol, 0.05% BSA
- Preservative
- 0.01% Sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Immunohistochemistry: 1/50-1/100
Target
- Alternative Names
- TYK1
- Gene ID
- 4058
- UniProt ID
- P29376
- Sequence Similarities
- Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
- Cellular Localization
- Cell membrane
- Post Translation Modifications
- Phosphorylated at tyrosine residues by autocatalysis, which activates kinase activity. (P29376-LTK_HUMAN)
Glycosylation at Asn257, Asn380, and Asn412 (NX_P29376 [NX_P29376-1])
Modification sites at PhosphoSitePlus (P29376)
Glycosylation from GlyGen (P29376) 3 sites
- Protein Refseq
- XP_011519859.1; XP_024305687.2; XP_047288455.1; XP_047288456.1; XP_047288457.1
- Function
- Receptor with a tyrosine-protein kinase activity.
Following activation by ALKAL1 or ALKAL2 ligands at the cell surface, transduces an extracellular signal into an intracellular response.
Ligand-binding to the extracellular domain induces tyrosine kinase activation, leading to activation of the mitogen-activated protein kinase (MAPK) pathway.
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Human Antibody Products
Rabbit Monoclonal Antibody Products
IgG Antibody Products
Antibody Magnetic Beads
Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0711CL | Anti-Human LTK Recombinant Antibody (FAM150A) | ELISA, FuncS, FC, WB, Activ, IP, SPR, IHC | Human antibody |
| TAB-0712CL | Anti-Human LTK Recombinant Antibody (FAM150B) | ELISA, FuncS, FC, WB, Activ, IP, IHC | Human antibody |
| TAB-0711CL-S(P) | Anti-Human LTK Recombinant Antibody scFv Fragment (FAM150A) | ELISA, FC | Human antibody |
| TAB-0711CL-F(E) | Anti-Human LTK Recombinant Antibody Fab Fragment (FAM150A) | ELISA, FC | Human antibody |
| TAB-0712CL-F(E) | Anti-Human LTK Recombinant Antibody Fab Fragment (FAM150B) | ELISA, FC | Human antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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