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MIB1
Loading...Anti-MIB1 Products
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, ELISA, FC, ICC, IF
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- Mouse Anti-NHP MIB1 Recombinant Antibody (clone 2A7B1) (VS-1024-XY323)
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- Species Reactivity: Human, Non-human primate
- Type: Mouse IgG1
- Application: WB, FC, ELISA
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: WB, IHC, ICC, IP
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- Mouse Anti-MIB1 Recombinant Antibody (clone 6A9C9) (VS7-0425-WR383)
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- Species Reactivity: Human, Monkey
- Type: Mouse IgG1
- Application: WB, ICC, FC
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For Research Use Only. Not For Clinical Use.
This gene encodes a protein containing multiple ankyrin repeats and RING finger domains that functions as an E3 ubiquitin ligase. The encoded protein positively regulates Notch signaling by ubiquitinating the Notch receptors, thereby facilitating their endocytosis. This protein may also promote the ubiquitination and degradation of death-associated protein kinase 1 (DAPK1).
Protein class
Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Oligodendrocyte precursor cells, Oligodendrocytes)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (REH)
Interaction
Interacts with CEP131 and PCM1.
Molecular function
Transferase
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