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NAMPT
This gene encodes a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein belongs to the nicotinic acid phosphoribosyltransferase (NAPRTase) family and is thought to be involved in many important biological processes, including metabolism, stress response and aging. This gene has a pseudogene on chromosome 10.
Protein class
Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins
Predicted location
Intracellular, Secreted (different isoforms)
Single cell type specificity
Cell type enhanced (Langerhans cells, Macrophages, Hepatocytes)
Immune cell specificity
Immune cell enriched (neutrophil)
Cell line specificity
Cell line enhanced (HHSteC, U-87 MG)
Interaction
Homodimer.
Molecular function
Cytokine, Glycosyltransferase, Transferase
More Types Infomation
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- Species Reactivity: Human
- Application: ELISA, WB
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: WB, IHC-P, ICC
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- Species Reactivity: Human
- Type: IgG
- Application: WB, IF, ICC, FC
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, IHC, ICC, FC, ELISA
- Mouse Anti-NAMPT Recombinant Antibody (clone 4E11C9) (VS3-XY1133)
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- Species Reactivity: Human
-
- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, ELISA
-
- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, ELISA
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For Research Use Only. Not For Clinical Use.