Anti-PDK2 Recombinant Antibody Products
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IHC, FC, IP
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: WB, IHC, ICC, FC, ELISA
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- Derivation: Mouse
- Species Reactivity: Human, Mouse
- Type: Mouse IgG1, κ
- Application: WB, IHC
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- Derivation: Rabbit
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, ELISA
- Mouse Anti-PDK2 Recombinant Antibody (clone 3F2C4) (VS3-XY1233)
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- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: IHC, ICC, FC
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IHC-P, IP
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IHC-P, ICC, IF, IP, FC
- Recombinant Mouse Anti-Human PDK2 Antibody (MOB-1050MZ)
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: WB
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: FC, ICC, IHC-P, WB
- Mouse Anti-PDK2 Recombinant Antibody (clone 3F2D7) (VS7-0425-WR588)
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- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: WB, FC
- Anti-PDK2 Immunohistochemistry Kit (VS-0325-XY1607)
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- Species Reactivity: Human
- Target: PDK2
- Application: IHC
- Anti-Mouse PDK2 Immunohistochemistry Kit (VS-0525-XY5292)
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- Species Reactivity: Human, Mouse, Rat
- Target: PDK2
- Application: IHC
- Anti-Human PDK2 Immunohistochemistry Kit (VS-0525-XY5291)
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- Species Reactivity: Human
- Target: PDK2
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Creative Biolabs is proud to present its cutting-edge anti-PDK2 recombinant antibody products, meticulously developed to meet the rigorous demands of global researchers. Our advanced antibody solutions offer unparalleled specificity and reliability, empowering your studies in metabolic regulation, cancer biology, and beyond. Experience the difference of premium quality and robust performance in your critical research.
PDK2: A Pivotal Target for Metabolic Disorders and Cancer Therapy
Pyruvate Dehydrogenase Kinase 2 (PDK2) is a crucial mitochondrial enzyme that phosphorylates and inactivates the pyruvate dehydrogenase complex (PDC), a key regulator of glucose metabolism. Extensive research highlights PDK2's significant role in shifting cellular metabolism from oxidative phosphorylation to glycolysis, a hallmark of many cancers and metabolic diseases like diabetes. Understanding and targeting PDK2 is therefore vital for developing novel therapeutic strategies for these pervasive conditions.
Alternative Names
Pyruvate dehydrogenase kinase isoform 2; pyruvate dehydrogenase lipoamide kinase isozyme 2; PDHK2; PDKII.
Background
This gene encodes a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010].
Enzymes, Metabolic proteins
Intracellular
Cell type enhanced (Proximal tubular cells, Proximal enterocytes)
Low immune cell specificity
Low cell line specificity
Homodimer, and heterodimer with PDK1. Interacts with the pyruvate dehydrogenase complex subunit DLAT, and is part of the multimeric pyruvate dehydrogenase complex that contains multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (DLAT, E2) and lipoamide dehydrogenase (DLD, E3).
Kinase, Transferase
Anti-PDK2 rAb Products
Our anti-PDK2 recombinant antibody products are engineered with superior precision, offering exceptional affinity and specificity for the PDK2 protein. Produced using advanced recombinant technology, these antibodies ensure lot-to-lot consistency and minimal batch variation, critical for reproducible research outcomes. Their high purity and robust performance make them ideal tools for a wide range of applications, from Western blotting to immunohistochemistry and functional assays.
| Cat. No. | Product Name | Target Species | Host Species | Applications |
| VS3-FY1120 | Recombinant Rabbit Anti-PDK2 Antibody (clone R01-6D8) | Human | Human IgG1 - kappa | WB, IHC-P, IP |
| MRO-1199-CN | Recombinant Rabbit Anti-PDK2 Monoclonal Antibody (JB66-93) | Human | Mouse IgG | WB, IHC, FC, IP |
| VS3-QX862 | Mouse Anti-PDK2 Recombinant Antibody (clone 180CT10.2.3) | Human, Mouse | Mouse IgG1, κ | WB, IHC |
| MOB-1050MZ | Recombinant Mouse Anti-Human PDK2 Antibody | Human | Mouse antibody | WB |
| VS3-XY3460 | Rabbit Anti-PDK2 Recombinant Antibody (clone R01-5X9) | Human, Mouse, Rat | Rabbit IgG | WB, IHC-P, ICC, IF, IP, FC |
Table 1. Featured anti-PDK2 recombinant antibody products at Creative Biolabs. Creative Quality Control
Creative Quality Control
At Creative Biolabs, quality is paramount. Our anti-PDK2 recombinant antibodies undergo rigorous, multi-faceted quality control measures, including comprehensive specificity testing, binding affinity validation, and functional assessments. Each product is meticulously characterized to guarantee optimal performance and reliability, providing researchers with complete confidence in their experimental results. This commitment ensures you receive only the highest-grade reagents for your valuable work.
Fig.1 WB analysis of anti-PDK2 antibody
(Cat# VS3-FY1120, Creative Biolabs).
Customer Reviews
Recombinant Rabbit Anti-PDK2 Antibody (clone R01-6D8) (VS3-FY1120)
Rabbit Anti-PDK2 Recombinant Antibody (clone R01-5X9) (VS3-XY3460)
Rabbit Anti-PDK2 Recombinant Antibody (clone R01-5X9) (VS3-XY3460)
rAb Production
The production of our anti-PDK2 recombinant antibodies leverages state-of-the-art expression systems and purification techniques, ensuring high yield and unmatched purity. Our streamlined, controlled manufacturing process adheres to stringent quality standards, minimizing contaminants and maximizing antibody integrity. This advanced production pipeline guarantees that every antibody delivered is of the highest possible quality, ready for your most demanding applications.
Featured Anti-PDK2 Recombinant Antibody Production Platforms
Fig.2 Milligram-scale anti-PDK2 recombinant antibody production.
Fig.3 Gram-scale anti-PDK2 recombinant antibody production.
rAb Modalities
Creative Biolabs offers anti-PDK2 recombinant antibodies in multiple modalities, including unconjugated, biotin-conjugated, and various fluorescent-labeled formats, providing versatility for diverse experimental designs.
Fig.4 Full-length anti-PDK2 recombinant antibody production and modalities.
Discover the transformative potential of Creative Biolabs' anti-PDK2 recombinant antibody products for your research. Our dedicated team is ready to assist you in selecting the ideal solution to accelerate your scientific breakthroughs. Contact us today to learn more about our comprehensive product portfolio and how we can support your next project.


PPAR Signaling Pathway