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PRKD2

Anti-PRKD2 Products
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: WB, FC, ICC, IF, IHC
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- Species Reactivity: Human
- Application: IHC-P, WB
- PE-HLA-A2/Human PRKD2 (RQASLSISV) MHC Tetramer (MHC-LC1898)
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- Class: Class I
- Antigen: PRKD2
- Antigen Species: Human
- Peptide: RQASLSISV
- Conjugate: PE
- APC-HLA-A2/Human PRKD2 (RQASLSISV) MHC Tetramer (MHC-LC1899)
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- Class: Class I
- Antigen: PRKD2
- Antigen Species: Human
- Peptide: RQASLSISV
- Conjugate: APC
- BV421-HLA-A2/Human PRKD2 (RQASLSISV) MHC Tetramer (MHC-LC1900)
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- Class: Class I
- Antigen: PRKD2
- Antigen Species: Human
- Peptide: RQASLSISV
- Conjugate: BV421
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- Species Reactivity: Human, Mouse
- Type: Rabbit IgG
- Application: WB, IF, IHC, FC
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IP
- AbPlus™ Anti-PRKD2 Magnetic Beads (VS-0724-YC1275) (VS-0724-YC1275)
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- Target: PRKD2
- Target Species: Human
- Application: IP, Protein Purification
- Anti-PRKD2 Immunohistochemistry Kit (VS-0325-XY1757)
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- Species Reactivity: Human, Mouse, Rat
- Target: PRKD2
- Application: IHC
- Anti-Mouse PRKD2 Immunohistochemistry Kit (VS-0525-XY5702)
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- Species Reactivity: Human, Mouse, Rat, Canine, Monkey
- Target: PRKD2
- Application: IHC
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: IP, WB
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More Infomation
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For Research Use Only. Not For Clinical Use.
The protein encoded by this gene belongs to the protein kinase D (PKD) family of serine/threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans-Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN.
Protein class
Enzymes, Metabolic proteins
Predicted location
Intracellular
Single cell type specificity
Low cell type specificity
Immune cell specificity
Low immune cell specificity
Cell line specificity
Cell line enhanced (U-266/84)
Interaction
Interacts (via C-terminus) with LCK (PubMed:19192391). Interacts (via N-terminal AP-rich region) with CIB1 isoform 2 (PubMed:23503467). Interacts (via N-terminus and zing-finger domain 1 and 2) with PRKCD in response to oxidative stress; the interaction is independent of PRKD2 tyrosine phosphorylation (PubMed:28428613).
Molecular function
Kinase, Serine/threonine-protein kinase, Transferase
More Types Infomation