BV421-HLA-A2/Human PRKD2 (RQASLSISV) MHC Tetramer (CAT#: MHC-LC1900)

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of PRKD2-derived peptide of RQASLSISV covering 526-534 and HLA-A2 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.

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MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.

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Disclaimer: Please note that the MHC reagents we offered have been produced with strict quality control (including gene sequencing, affinity purification, SDS-PAGE analysis, and verification of biotinylation), but many have not been confirmed to stain or activate specific T cells.

We require custom production
  • Datasheet
  • MSDS
  • COA

Specifications

  • Allele
  • HLA-A2
  • Class
  • Class I
  • MHC Species
  • Human
  • Antigen
  • PRKD2
  • Antigen Species
  • Human
  • Peptide
  • RQASLSISV
  • Range
  • 526-534
  • Conjugate
  • BV421
  • Application
  • FCM

Target

  • Antigen Introduction
  • The protein encoded by this gene belongs to the protein kinase D (PKD) family of serine/threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans-Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN. Alternative splicing results in multiple transcript variants encoding different isoforms.
  • Alternative Names
  • PRKD2; protein kinase D2; PKD2; HSPC187; nPKC-D2

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