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For Research Use Only. Not For Clinical Use.
Disease related genes, Human disease related genes
Intracellular
Group enriched (Late spermatids, Early spermatids)
Not detected in immune cells
Cell line enriched (AN3-CA)
Forms homodimers (in vitro) (By similarity). Homopolymerizes into a filamentous network (in vitro) (PubMed:15446584). Forms heterodimers with NEFL, NEFM or NEFH (in vitro) (By similarity). Interacts with DST (via C-terminus) (By similarity). Interacts with RAB7A; the interaction is direct (PubMed:23179371). Interacts with PRKCE (via phorbol-ester/DAG-type 2 domain) (PubMed:18408015).