Disease related genes, Human disease related genes
Intracellular
Group enriched (Late spermatids, Early spermatids)
Not detected in immune cells
Cell line enriched (AN3-CA)
Forms homodimers (in vitro) (By similarity). Homopolymerizes into a filamentous network (in vitro) (PubMed:15446584). Forms heterodimers with NEFL, NEFM or NEFH (in vitro) (By similarity). Interacts with DST (via C-terminus) (By similarity). Interacts with RAB7A; the interaction is direct (PubMed:23179371). Interacts with PRKCE (via phorbol-ester/DAG-type 2 domain) (PubMed:18408015).
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For Research Use Only. Not For Clinical Use.