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PTPRZ1
Loading...Anti-PTPRZ1 Products
- Anti-PTPRZ1 immunotoxin 7E4B11 (IgG)-Sap (AGTO-G058S)
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Function study
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- Chicken Anti-PTPRZ1 Polyclonal IgY (BRD-0477MZ)
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- Species Reactivity: Human
- Type: Chicken antibody
- Application: WB
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- Anti-PTPRZ1 Immunohistochemistry Kit (VS-0525-XY5884)
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- Species Reactivity: Human
- Target: PTPRZ1
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes a member of the receptor protein tyrosine phosphatase family. Expression of this gene is restricted to the central nervous system (CNS), and it may be involved in the regulation of specific developmental processes in the CNS. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Protein class
Enzymes, Metabolic proteins, Plasma proteins
Predicted location
Membrane, Secreted (different isoforms)
Single cell type specificity
Cell type enriched (Oligodendrocyte precursor cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Group enriched (AF22, NTERA-2, WM-115)
Interaction
The carbonic-anhydrase like domain interacts with CNTN1 (contactin) (PubMed:20133774). Interacts with PTN (PubMed:16814777). Interaction with PTN promotes formation of homooligomers; oligomerization impairs phosphatase activity (By similarity). Interacts (via chondroitin sulfate chains) with MDK (via C-terminal); this interaction is inhibited by PTN; this interaction promotes neuronal migration (By similarity).
Molecular function
Hydrolase, Protein phosphatase
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