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RAB1B
Loading...Anti-RAB1B Products
- Mouse Anti-RAB1B Recombinant Antibody (VS3-WK1144) (VS3-WK1144)
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- Derivation: Mouse
- Species Reactivity: Human, Mouse, Rat
- Type: Mouse IgG
- Application: WB
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- Mouse Anti-RAB1B Recombinant Antibody (VS3-FY2849) (VS3-FY2849)
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- Species Reactivity: Human, Mouse, Rat
- Type: Mouse IgG
- Application: WB, FC
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- Mouse Anti-RAB1B Recombinant Antibody (clone 7A12G2) (VS7-0425-WR736)
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- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: IHC, FC
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- Anti-RAB1B Immunohistochemistry Kit (VS-0325-XY1846)
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- Species Reactivity: Human, Mouse, Rat
- Target: RAB1B
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Members of the RAB protein family, such as RAB1B, are low molecular mass monomeric GTPases localized on the cytoplasmic surfaces of distinct membrane-bound organelles. RAB1B functions in the early secretory pathway and is essential for vesicle transport between the endoplasmic reticulum (ER) and Golgi (Chen et al., 1997 [PubMed 9030196]; Alvarez et al., 2003 [PubMed 12802079]).[supplied by OMIM, Jan 2009]
Protein class
Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Low cell type specificity
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Interacts with MICAL1 and MICAL2 (PubMed:15694364, PubMed:27552051). Interacts (in GTP-bound form) with MICALCL, MICAL1 and MILCAL3 (PubMed:15694364, PubMed:27552051). Interacts with GDI1; the interaction requires the GDP-bound state (PubMed:8836150, PubMed:11389151). Interacts with CHM/REP1; the interaction requires the GDP-bound form and is necessary for prenylation by GGTase II (PubMed:9437002, PubMed:11389151). Interacts with RabGAP TBC1D20 (PubMed:23236136). Interacts (in GDP-bound form) with lipid phosphatase MTMR6 (via GRAM domain); the interaction regulates MTMR6 recruitment to the endoplasmic reticulum-Golgi intermediate compartment (PubMed:23188820). Interacts (in GDP-bound form) with lipid phosphatase MTMR7 (By similarity). (Microbial infection) Interacts with L. pneumophila AnkX (PubMed:21822290, PubMed:22307087). Interacts with L. pneumophila Lem3 (PubMed:22158903, PubMed:22307087). Interacts with L. pneumophila SidD (PubMed:21734656, PubMed:21680813). Interacts with L. pneumophila DrrA (PubMed:20064470, PubMed:20651120).
Molecular function
Hydrolase
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