Mouse Anti-RAB1B Recombinant Antibody (VS3-FY2849)
CAT#: VS3-FY2849
This anti-RAB1B antibody is a mouse recombinant monoclonal antibody that binds to human RAB1B protein. It cross-reacts with mouse, rat species. The calculated molecular weight of the protein is about 22.2 kDa. The monoclonal antibody can be used in the area of Hypotrichosis 3 and Legionnaire Disease. This monoclonal antibody is suitable for employment in Western Blot (1/500-1/2000) and Flow cytometry (1/10-1/25).
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to endoplasmic reticulum & the Golgi apparatus.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10225/931_C10_3_selected.jpg
Normal Tissue
Figure 2 IHC staining of human bone marrow
Immunohistochemical staining of human bone marrow shows strong cytoplasmic positivity in bone marrow poietic cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10225/ihc_selected.jpg
Normal Tissue
Figure 3 Duodenum
Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/56141/143802_A_8_2.jpg
Normal Tissue
Figure 4 Kidney
Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/56141/143802_A_8_5.jpg
Normal Tissue
Figure 5 Testis
Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/56141/143802_A_6_6.jpg
RNA Expression
Figure 6 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000174903-RAB1B
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Specifications
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human, Mouse and Rat RAB1B
- Species Reactivity
- Human, Mouse, Rat
- Applications
- Western Blot, Flow cytometry
- Conjugate
- Unconjugated, FITC
- MW
- The molecular weight of the target protein is approximately 22.2 kDa.
- Related Disease
- Hypotrichosis 3 and Legionnaire Disease
Product Property
- Clonality
- Monoclonal Antibody
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/2000
Flow cytometry: 1/10-1/25
Target
- Alternative Names
- RAB1B, Member RAS Oncogene Family
- Gene ID
- 81876
- UniProt ID
- Q9H0U4
- Sequence Similarities
- Belongs to the small GTPase superfamily. Rab family.
- Cellular Localization
- Cytoplasm
Membrane
Lipid-anchor
Cytoplasmic side
Preautophagosomal structure membrane
Lipid-anchor
Cytoplasmic side
Cytoplasm, perinuclear region
- Post Translation Modifications
- Modification sites at PhosphoSitePlus (Q9H0U4)
Modification sites at neXtProt (NX_Q9H0U4)
Glycosylation from GlyGen (Q9H0U4) 1 site, 1 O-linked glycan (1 site)
- Function
- Plays a role in the initial events of the autophagic vacuole development which take place at specialized regions of the endoplasmic reticulum (PubMed:20545908).
Regulates vesicular transport between the endoplasmic reticulum and successive Golgi compartments (By similarity).
Required to modulate the compacted morphology of the Golgi.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "RAB1B"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1741CT | Recombinant Mouse anti-Human RAB1B Monoclonal antibody (1B2) | ELISA, WB | |
| VS3-WK127 | Mouse Anti-RAB1B Recombinant Antibody (clone G2-A12) | WB, ELISA | Mouse IgG2b |
| VS3-WK1144 | Mouse Anti-RAB1B Recombinant Antibody (VS3-WK1144) | WB | Mouse IgG |
| VS7-0425-WR736 | Mouse Anti-RAB1B Recombinant Antibody (clone 7A12G2) | IHC, FC | Mouse IgG2b |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1846 | Anti-RAB1B Immunohistochemistry Kit | IHC |
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