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RSPO2

Anti-RSPO2 Products

Recombinant Rat Anti-RSPO2 Antibody (CBL669) (NEUT-1923CQ)
- Species Reactivity: Human
- Type: IgG1
- Application: Neut
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Human Anti-RSPO2 Recombinant Antibody (HPAB-0307-WJ) (HPAB-0307-WJ)
- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ELISA, FC, Block, Inhib, FuncS
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Human Anti-RSPO2 Recombinant Antibody Fab Fragment (TAB-0232CL-F(E)) (TAB-0232CL-F(E))
- Type: Humanized Antibody
- Application: ELISA, Inhib, Block, FuncS, In vivo
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Human Anti-RSPO2 Recombinant Antibody Fab Fragment (TAB-0233CL-F(E)) (TAB-0233CL-F(E))
- Type: Humanized Antibody
- Application: ELISA, Inhib, Block, FuncS, In vivo
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Human Anti-RSPO2 Recombinant Antibody scFv Fragment (TAB-0232CL-S(P)) (TAB-0232CL-S(P))
- Type: Humanized Antibody
- Application: ELISA, Inhib, Block, FuncS, In vivo
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Human Anti-RSPO2 Recombinant Antibody scFv Fragment (TAB-0233CL-S(P)) (TAB-0233CL-S(P))
- Type: Humanized Antibody
- Application: ELISA, Inhib, Block, FuncS, In vivo
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Human Anti-RSPO2 Recombinant Antibody (TAB-0232CL) (TAB-0232CL)
- Type: Humanized Antibody
- Application: ELISA, Inhib, Block, FuncS, In vivo
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Human Anti-RSPO2 Recombinant Antibody (TAB-0233CL) (TAB-0233CL)
- Type: Humanized Antibody
- Application: ELISA, Inhib, Block, FuncS, In vivo
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Mouse Anti-RSPO2 Recombinant Antibody (VS-0224-XY106) (VS-0224-XY106)
- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: WB, IHC
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Mouse Anti-RSPO2 Recombinant Antibody scFv Fragment (TAB-0226CL-S(P)) (TAB-0226CL-S(P))
- Application: ELISA, Inhib, Block, FuncS, In vivo
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Mouse Anti-RSPO2 Recombinant Antibody scFv Fragment (TAB-0227CL-S(P)) (TAB-0227CL-S(P))
- Application: ELISA, Inhib, Block, FuncS, In vivo
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Mouse Anti-RSPO2 Recombinant Antibody scFv Fragment (TAB-0228CL-S(P)) (TAB-0228CL-S(P))
- Application: ELISA, Inhib, Block, FuncS, In vivo
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Mouse Anti-RSPO2 Recombinant Antibody scFv Fragment (TAB-0229CL-S(P)) (TAB-0229CL-S(P))
- Application: ELISA, Inhib, Block, FuncS, In vivo
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Mouse Anti-RSPO2 Recombinant Antibody Fab Fragment (TAB-0226CL-F(E)) (TAB-0226CL-F(E))
- Application: ELISA, Inhib, Block, FuncS, In vivo
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Mouse Anti-RSPO2 Recombinant Antibody Fab Fragment (TAB-0227CL-F(E)) (TAB-0227CL-F(E))
- Application: ELISA, Inhib, Block, FuncS, In vivo
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Mouse Anti-RSPO2 Recombinant Antibody scFv Fragment (TAB-0230CL-S(P)) (TAB-0230CL-S(P))
- Application: ELISA, Inhib, Block, FuncS, In vivo
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Mouse Anti-RSPO2 Recombinant Antibody scFv Fragment (TAB-0231CL-S(P)) (TAB-0231CL-S(P))
- Application: ELISA, Inhib, Block, FuncS, In vivo
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Human Anti-RSPO2 Recombinant Antibody; scFv Fragment (HPAB-0307-WJ-S(P)) (HPAB-0307-WJ-S(P))
- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: ELISA, FC
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Human Anti-RSPO2 Recombinant Antibody; Fab Fragment (HPAB-0307-WJ-F(E)) (HPAB-0307-WJ-F(E))
- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, FC
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Mouse Anti-RSPO2 Recombinant Antibody (TAB-0226CL) (TAB-0226CL)
- Application: ELISA, Inhib, Block, FuncS, In vivo
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Mouse Anti-RSPO2 Recombinant Antibody (TAB-0227CL) (TAB-0227CL)
- Application: ELISA, Inhib, Block, FuncS, In vivo
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Mouse Anti-RSPO2 Recombinant Antibody (TAB-0228CL) (TAB-0228CL)
- Application: ELISA, Inhib, Block, FuncS, In vivo
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Mouse Anti-RSPO2 Recombinant Antibody (TAB-0229CL) (TAB-0229CL)
- Application: ELISA, Inhib, Block, FuncS, In vivo
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Mouse Anti-RSPO2 Recombinant Antibody (TAB-0230CL) (TAB-0230CL)
- Application: ELISA, Inhib, Block, FuncS, In vivo
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Mouse Anti-RSPO2 Recombinant Antibody (TAB-0231CL) (TAB-0231CL)
- Application: ELISA, Inhib, Block, FuncS, In vivo
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Mouse Anti-RSPO2 Recombinant Antibody; scFv Fragment (TAB-348CT-S(P)) (TAB-348CT-S(P))
- Derivation: Mouse hybridoma cell lines
- Species Reactivity: Mouse, Cynomolgus
- Type: Mouse scFv
- Application: WB, ELISA, Neut, FC, IHC, IP
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Mouse Anti-RSPO2 Recombinant Antibody; scFv Fragment (TAB-349CT-S(P)) (TAB-349CT-S(P))
- Derivation: Mouse hybridoma cell lines
- Species Reactivity: Mouse, Cynomolgus
- Type: Mouse scFv
- Application: WB, ELISA, Neut, FC, IHC, IP
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Mouse Anti-RSPO2 Recombinant Antibody; Fab Fragment (TAB-346CT-F(E)) (TAB-346CT-F(E))
- Derivation: Mouse hybridoma cell lines
- Species Reactivity: Mouse, Cynomolgus
- Type: Mouse Fab
- Application: WB, ELISA, Neut, FC, IHC, IP
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Mouse Anti-RSPO2 Recombinant Antibody; Fab Fragment (TAB-347CT-F(E)) (TAB-347CT-F(E))
- Derivation: Mouse hybridoma cell lines
- Species Reactivity: Mouse, Cynomolgus
- Type: Mouse Fab
- Application: WB, ELISA, Neut, FC, IHC, IP
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Mouse Anti-RSPO2 Recombinant Antibody; Fab Fragment (TAB-348CT-F(E)) (TAB-348CT-F(E))
- Derivation: Mouse hybridoma cell lines
- Species Reactivity: Mouse, Cynomolgus
- Type: Mouse Fab
- Application: WB, ELISA, Neut, FC, IHC, IP
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Mouse Anti-RSPO2 Recombinant Antibody; Fab Fragment (TAB-349CT-F(E)) (TAB-349CT-F(E))
- Derivation: Mouse hybridoma cell lines
- Species Reactivity: Mouse, Cynomolgus
- Type: Mouse Fab
- Application: WB, ELISA, Neut, FC, IHC, IP
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Mouse Anti-RSPO2 Recombinant Antibody (TAB-346CT) (TAB-346CT)
- Derivation: Mouse hybridoma cell lines
- Species Reactivity: Mouse, Cynomolgus
- Type: Mouse IgG
- Application: WB, ELISA, Neut, FC, IHC, IP
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Mouse Anti-RSPO2 Recombinant Antibody (TAB-347CT) (TAB-347CT)
- Derivation: Mouse hybridoma cell lines
- Species Reactivity: Mouse, Cynomolgus
- Type: Mouse IgG
- Application: WB, ELISA, Neut, FC, IHC, IP
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Mouse Anti-RSPO2 Recombinant Antibody (TAB-348CT) (TAB-348CT)
- Derivation: Mouse hybridoma cell lines
- Species Reactivity: Mouse, Cynomolgus
- Type: Mouse IgG
- Application: WB, ELISA, Neut, FC, IHC, IP
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Mouse Anti-RSPO2 Recombinant Antibody (TAB-349CT) (TAB-349CT)
- Derivation: Mouse hybridoma cell lines
- Species Reactivity: Mouse, Cynomolgus
- Type: Mouse IgG
- Application: WB, ELISA, Neut, FC, IHC, IP
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Mouse Anti-RSPO2 Recombinant Antibody; scFv Fragment (TAB-346CT-S(P)) (TAB-346CT-S(P))
- Derivation: Mouse hybridoma cell lines
- Species Reactivity: Mouse, Cynomolgus
- Type: Mouse scFv
- Application: WB, ELISA, Neut, FC, IHC, IP
Compare

Mouse Anti-RSPO2 Recombinant Antibody; scFv Fragment (TAB-347CT-S(P)) (TAB-347CT-S(P))
- Derivation: Mouse hybridoma cell lines
- Species Reactivity: Mouse, Cynomolgus
- Type: Mouse scFv
- Application: WB, ELISA, Neut, FC, IHC, IP
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Mouse Anti-RSPO2 Recombinant Antibody Fab Fragment (TAB-0228CL-F(E)) (TAB-0228CL-F(E))
- Application: ELISA, Inhib, Block, FuncS, In vivo
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Mouse Anti-RSPO2 Recombinant Antibody Fab Fragment (TAB-0229CL-F(E)) (TAB-0229CL-F(E))
- Application: ELISA, Inhib, Block, FuncS, In vivo
Compare

Mouse Anti-RSPO2 Recombinant Antibody Fab Fragment (TAB-0230CL-F(E)) (TAB-0230CL-F(E))
- Application: ELISA, Inhib, Block, FuncS, In vivo
Compare

Mouse Anti-RSPO2 Recombinant Antibody Fab Fragment (TAB-0231CL-F(E)) (TAB-0231CL-F(E))
- Application: ELISA, Inhib, Block, FuncS, In vivo
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Anti-RSPO2 Immunohistochemistry Kit (VS-0525-XY6252)
- Species Reactivity: Human
- Target: RSPO2
- Application: IHC
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For Research Use Only. Not For Clinical Use.

This gene encodes a member of the R-spondin family of proteins. These proteins are secreted ligands of leucine-rich repeat containing G protein-coupled receptors that enhance Wnt signaling through the inhibition of ubiquitin E3 ligases. A chromosomal translocation including this locus that results in the formation of a gene fusion has been identified in multiple human cancers. Alternative splicing results in multiple transcript variants.

Protein class

Cancer-related genes, Disease related genes, Human disease related genes

Predicted location

Intracellular, Secreted (different isoforms)

Single cell type specificity

Group enriched (Inhibitory neurons, Excitatory neurons)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (HEK93, U-266/70)

Interaction

Interacts with WNT1 (By similarity). Binds heparin (By similarity). Interacts with LGR4, LGR5 and LGR6 (PubMed:21909076, PubMed:21727895, PubMed:22615920, PubMed:29769720). Interacts with E3 ubiquitin ligases RNF43 and ZNRF3 (PubMed:29769720).

Molecular function

Developmental protein, Heparin-binding

More Types Infomation