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STXBP1

Anti-STXBP1 Recombinant Antibody Products

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For Research Use Only. Not For Clinical Use.


This gene encodes a syntaxin-binding protein. The encoded protein appears to play a role in release of neurotransmitters via regulation of syntaxin, a transmembrane attachment protein receptor.
Protein class

Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Transporters

Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Cell type enhanced (Excitatory neurons, Inhibitory neurons, Cone photoreceptor cells, Rod photoreceptor cells, Bipolar cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (SCLC-21H, SK-MEL-30)

Interaction

Interacts with SYTL4 (By similarity). Interacts with STX1A (PubMed:12730201). Interacts with alpha-synuclein/SNCA; this interaction controls SNCA self-replicating aggregation (PubMed:27597756). Interacts with RAB3A; this interaction promotes RAB3A dissociation from the vesicle membrane (By similarity). Interacts with CABP5 (By similarity).

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