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TET2
Loading...Anti-TET2 Products
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2b, κ
- Application: WB, IP, IF, ELISA
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- Mouse Anti-TET2 Recombinant Antibody (VS3-FY2890) (VS3-FY2890)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, IHC, ICC, FC, ELISA
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- Mouse Anti-TET2 Recombinant Antibody (clone 5H8B3) (VS7-0425-WR964)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: FC
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- Mouse Anti-TET2 Recombinant Antibody (clone 5H8C7) (VS7-0425-WR965)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, IHC, ICC, FC
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- Anti-TET2 Immunohistochemistry Kit (VS-0525-XY7177)
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- Species Reactivity: Human
- Target: TET2
- Application: IHC
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More Infomation
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For Research Use Only. Not For Clinical Use.
Background
The protein encoded by this gene is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. The encoded protein is involved in myelopoiesis, and defects in this gene have been associated with several myeloproliferative disorders. Two variants encoding different isoforms have been found for this gene.
Protein class
Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Oligodendrocytes, Oligodendrocyte precursor cells)
Immune cell specificity
Immune cell enhanced (neutrophil)
Cell line specificity
Low cell line specificity
Interaction
Interacts with HCFC1 and OGT.
Molecular function
Chromatin regulator, Dioxygenase, DNA-binding, Oxidoreductase
More Types Infomation