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    Mouse Anti-TET2 Recombinant Antibody (clone 5H8C7) (CAT#: VS7-0425-WR965)

    This product is a mouse IgG1 antibody that binds to human TET2. The antibody 5H8C7 can be used for WB, IHC, ICC, and FC assays.

    Specific Inquiry
    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    • Formats:

    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
    Endotoxin :
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    Conjugation :
    Fc Engineering :
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    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location
    Figure 1 IF staining of human cell line A-431
    Figure 1 IF staining of human cell line A-431
    (Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/43135/if_selected.jpg
    Normal Tissue
    Figure 2 IHC staining of human urinary bladder
    Figure 2 IHC staining of human urinary bladder
    (Immunohistochemical staining of human urinary bladder shows strong nuclear positivity in urothelial cells.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/43135/ihc_selected.jpg
    Figure 3 Cerebral cortex
    Figure 3 Cerebral cortex
    (Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear Glial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/43135/95044_B_8_5.jpg
    Figure 4 Colon
    Figure 4 Colon
    (Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/43135/95044_A_8_3.jpg
    Figure 5 Liver
    Figure 5 Liver
    (Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: nuclear Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/43135/95044_A_8_4.jpg
    Figure 6 Kidney
    Figure 6 Kidney
    (Cells in glomeruli Staining: High Intensity: Strong Quantity:>75% Location: Nuclear Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/43135/95044_A_8_5.jpg
    Figure 7 Testis
    Figure 7 Testis
    (Cells in seminiferous ducts Staining: High Intensity: Strong Quantity: 75%-25% Location: Nuclear Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/43135/95044_A_4_6.jpg
    Figure 8 Bone marrow
    Figure 8 Bone marrow
    (Hematopoietic cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/43135/95044_B_6_4.jpg
    Figure 9 Lymph node
    Figure 9 Lymph node
    (Germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Non-germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/43135/95044_A_9_8.jpg
    RNA Expression
    Figure 10 RNA cell line category: Low cell line specificity
    Figure 10 RNA cell line category: Low cell line specificity
    (Cell lines ordered by descending RNA expression order)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000168769-TET2

    Specifications

    • Immunogen
    • Recombinant human TET2 fragment expressed in E. Coli.
    • Host Species
    • Mouse
    • Type
    • Mouse IgG1
    • Specificity
    • Human TET2
    • Species Reactivity
    • Human
    • Clone
    • 5H8C7
    • Molecule Class
    • Methylcytosine Dioxygenase
    • Applications
    • WB, IHC, ICC, FC
    • Conjugate
    • Unconjugated
    • Related Disease
    • Polycythemia vera (PV); Myelodysplastic syndrome (MDS); Immunodeficiency 75 with lymphoproliferation (IMD75)

    Product Property

    • Clonality
    • Monoclonal
    • Purity
    • >95% as determined by SDS-PAGE and SEC-HPLC analysis
    • Format
    • Liquid
    • Concentration
    • Please refer to the vial label for the specific concentration.
    • Buffer
    • PBS
    • Preservative
    • 0.05% sodium azide
    • Storage
    • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
    • Shipping
    • Ice packs

    Applications

    • Application Notes
    • Western Blot: 1:500 - 1:2000
      Immunohistochemistry-Paraffin: 1:200 - 1:1000
      Immunocytochemistry: 1:200 - 1:1000
      Flow Cytometry: 1:200 - 1:400
      Enzyme-linked Immunosorbent Assay: 1:10000

    Target

    • Alternative Names
    • TET2; EC 1.14.11.n2; Tet Oncogene Family Member 2; Tet Methylcytosine Dioxygenase 2; KIAA1546; Methylcytosine Dioxygenase TET2
    • Long Name
    • Tet Methylcytosine Dioxygenase 2
    • Cellular Localization
    • Chromosome; Nucleus
    • Post Translation Modifications
    • Glycoprotein; Isopeptide bond; Methylation; Phosphoprotein; Ubl conjugation
    • Function
    • Chromatin regulator; Dioxygenase; DNA-binding; Oxidoreductase

    Recommended Products

    Isotype Control

    Secondary Antibody

    Reconstitution Buffer

    Recommended Dilution Buffer

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "TET2"

    Select a product category from the dropdown menu below to view related products.
    Please select product type
    IgG Antibody Products Cancer Stem Cell Biomarker Specific Antibody Products
    CAT Product Name Application Type
    MOB-3594z Mouse Anti-TET2 Recombinant Antibody (clone 31B4) WB, IP, IF, ELISA Mouse IgG2b, κ
    VS3-FY2890 Mouse Anti-TET2 Recombinant Antibody (VS3-FY2890) WB, IHC, ICC, FC, ELISA Mouse IgG
    VS7-0425-WR964 Mouse Anti-TET2 Recombinant Antibody (clone 5H8B3) FC Mouse IgG1

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