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Anti-TNFRSF18 Products

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For Research Use Only. Not For Clinical Use.


Creative Biolabs provides a comprehensive selection of validated anti-TNFRSF18 recombinant antibodies. Leveraging our advanced platform, these antibodies are engineered to exhibit exceptional specificity, stability, and efficacy, making them indispensable tools for advancing targeted therapeutic development.

TNFRSF18: A Promising Target for Cancer Immunotherapy

The TNFRSF18 gene encodes the GITR protein, a member of the tumor necrosis factor receptor superfamily (TNFRSF) characterized by cysteine-rich repeats in its cytoplasmic domain. GITR shares structural similarities with other TNFRSF members like CD137, OX40, and CD27. While GITR signaling can enhance anti-tumor and anti-infective immune responses, it can also contribute to autoimmune diseases. The differential effects of GITR signaling depend on its expression levels in various immune cell types. Given its potential to modulate immune responses, GITR has emerged as a promising target for cancer immunotherapy.

Alternative Names

GITR; CD357; GITR-D; ENERGEN; TNF receptor superfamily member 18; tumor necrosis factor receptor superfamily member 18.

Anti-TNFRSF18 rAb Products

Creative Biolabs provides a comprehensive portfolio of recombinant anti-TNFRSF18 antibodies, meticulously engineered to ensure optimal specificity and affinity. These antibodies, available in various formats, are ideal for a wide range of applications, including fundamental research and therapeutic development. By leveraging our advanced platform, we offer high-quality tools to advance the understanding of immunology, cancer biology, and related fields.

Table 1. Featured anti-TNFRSF18 recombinant antibody products at Creative Biolabs.

Cat. No. Product Name Target Species Host Species Applications
AFC-606CL Afuco™ Anti-Human TNFRSF18 ADCC Recombinant Antibody (TRX518), ADCC Enhanced Human Humanized ADCC
TAB-629CL Human Anti-TNFRSF18 Recombinant Antibody (TAB-629CL) Human Human IgG Activ
TAB-098CQ-F(E) Human Anti-TNFRSF18 Recombinant Antibody; Fab Fragment (TAB-098CQ-F(E)) Human Humanized Fab ELISA, FC, WB
TAB-099CQ Human Anti-TNFRSF18 Recombinant Antibody (TAB-099CQ) Human Human IgG ELISA, FC
TAB-104CQ Mouse Anti-TNFRSF18 Recombinant Antibody (TAB-104CQ) Human, Cynomolgus monkey Mouse IgG ELISA, FC

Creative Quality Control

Creative Biolabs is a premier provider of high-quality anti-TNFRSF18 recombinant antibodies that undergo rigorous quality control measures. Our state-of-the-art facilities and experienced scientists ensure that each antibody is meticulously engineered to target TNFRSF18 with precision. Through stringent testing and validation processes, we guarantee that our products exhibit exceptional specificity, strong binding affinity, and optimal performance in a variety of research applications.

Fig.1 SDS-PAGE analysis. (Creative Biolabs Original)Fig.1 SDS-PAGE analysis of anti-TNFRSF18 antibody
(Cat# AFC-606CL, Creative Biolabs).

Fig.2 WB analysis. (Creative Biolabs Original)Fig.2 WB analysis of anti-TNFRSF18 antibody
(Cat# AFC-606CL, Creative Biolabs).

Fig.3 ELISA analysis. (Creative Biolabs Original)Fig.3 ELISA analysis of anti-TNFRSF18 antibody
(Cat# AFC-606CL, Creative Biolabs).

Fig.4 SDS-PAGE analysis. (Creative Biolabs Original)Fig.4 SDS-PAGE analysis of anti-TNFRSF18 antibody
(Cat# TAB-099CQ, Creative Biolabs).

Customer Reviews

Excellent
Kn***e
Mouse Anti-TNFRSF18 Recombinant Antibody (TAB-104CQ) (CAT#: TAB-104CQ)
I've been using the anti-TNFRSF18 antibody from Creative Biolabs a few times now, and I'm always amazed by how well it works. Because of the antibody's exceptional sensitivity and specificity, TNFRSF18 can be reliably detected and quantified in my studies. Creative Biolabs also has an excellent technical support team that is always available to answer inquiries or address problems.
21/Sep/2023
Excellent
User 188*****5
Human Anti-TNFRSF18 Recombinant Antibody (TAB-099CQ) (CAT#: TAB-099CQ)
I recently incorporated Creative Biolabs' anti-TNFRSF18 antibody into my research project, and it has significantly enhanced the quality of my results. The antibody's high affinity and specificity have allowed me to achieve precise and reproducible data. The product arrived promptly and was well-packaged. I'm truly satisfied with this purchase.
14/Oct/2023
Excellent
Ri***s
Human Anti-TNFRSF18 Recombinant Antibody (TAB-629CL) (CAT#: TAB-629CL)
I was initially skeptical about trying a new supplier for my anti-TNFRSF18 antibody, but Creative Biolabs exceeded my expectations. The antibody performed exceptionally well in my activity investigation experiments. The technical support team provided valuable guidance on optimal experimental conditions, ensuring the success of my research. I am very pleased with the quality of the product and the level of customer service.
9/Jun/2024

rAb Production

Creative Biolabs leverages advanced genetic engineering to produce high-quality anti-TNFRSF18 antibodies, ensuring a reliable supply for diverse research applications.

Featured Anti-TNFRSF18 Recombinant Antibody Production PlatformsFig.5 Milligram-scale. (Creative Biolabs Original)
Fig.5 Milligram-scale anti-TNFRSF18 recombinant antibody production.

Fig.6 Gram-scale. (Creative Biolabs Original)Fig.6 Gram-scale anti-TNFRSF18 recombinant antibody production.

rAb Modalities

Creative Biolabs provides a broad spectrum of high-quality anti-TNFRSF18 recombinant antibodies to meet global research demands.

Fig.7 TNFRSF18 antibody production and modalities. (Creative Biolabs Original)Fig.7 Full-length anti-TNFRSF18 recombinant antibody production and modalities.

TNFRSF18-Targeted Drug Information

Table 2. Public drug targeting TNFRSF18.

Highest Phase Mechanism of Action Product Category Condition Organization
Bristol-Myers Squibb (Originator) Phase I/II Agonist Antibodies
Cancer Immunotherapy
Human Monoclonal Antibodies
Cancer, metastatic
Cancer, solid tumor
GITR, Inc. (Leap Therapeutics)
Leap Therapeutics
Tolerx (Originator)
Phase I/II Agonist Antibodies
Cancer Immunotherapy
Humanized Monoclonal Antibodies
Cancer
Cancer, breast
Cancer, ovary
Cancer, prostate (castration-resistant), metastatic
Cancer, solid tumor
Immunological Disorders
Infection, viral
Melanoma
Melanoma, malignant
Triple negative breast cancer
Lilly (Originator) Phase I Antibodies Atopic dermatitis
Regeneron (Originator) Phase I Cancer Immunotherapy
Monoclonal Antibodies
Cancer, head and neck (squamous cell carcinoma)
Cancer, solid tumor
Novartis (Originator) Phase I Antibodies
Cancer Immunotherapy
Cancer, solid tumor
Lymphoma
Amgen (Originator) Phase I Cancer Immunotherapy
Monoclonal Antibodies
Cancer, solid tumor
Merck & Co (Originator)
Merck & Co. (Merck & Co)
Phase I Agonist Antibodies
Cancer Immunotherapy
Humanized Monoclonal Antibodies
Cancer, solid tumor
Glioblastoma multiforme
First Affiliated Hospital Zhengzhou Univ
Fudan University
Kyoto University (Originator)
Preclinical Murine Monoclonal Antibodies Ulcerative colitis
University of Southampton (Originator) Preclinical Cancer Immunotherapy
Monoclonal Antibodies
Cancer
Shanghai ChemPartner (Originator)
Shanghai Pharmaexplorer (Originator)
Preclinical Cancer Immunotherapy
Murine Monoclonal Antibodies
Cancer, colorectal

(Disclaimer: The information in this table is just for knowledge sharing and not for marketing or sales purposes.)

If you want to know more details and inquire about our anti-TNFRSF18 recombinant antibody products, please get in touch with us at any time.

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