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TNFRSF1B
Loading...Anti-TNFRSF1B Products
- Rat Anti-TNFRSF1B Recombinant Antibody (NEUT-2153CQ) (NEUT-2153CQ)
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- Species Reactivity: Human
- Type: Rat IgG2a, κ
- Application: FC, Neut
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- Hamster Anti-Tnfrsf1b Recombinant Antibody (NEUT-2155CQ) (NEUT-2155CQ)
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- Species Reactivity: Mouse
- Type: Hamster IgG
- Application: FC, IP, Block
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- Mouse Anti-TNFRSF1B Recombinant Antibody (clone 32) (HPAB-1550WJ)
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- Derivation: Hybridoma
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, WB
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- Mouse Anti-TNFRSF1B Agonistic Antibody (clone MR2-1) (VS-0724-XY49)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: FC, IHC, Agonistic assays
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- Anti-TNFRSF1B Recombinant Antibody (VS-0824-YJ45) (VS-0824-YJ45)
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- Species Reactivity: Human
- Application: ELISA, WB, Inhib
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- AbPlus™ Anti-Tnfrsf1b Magnetic Beads (VS-0724-YC1501) (VS-0724-YC1501)
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- Target: Tnfrsf1b
- Target Species: Mouse
- Application: IP, Protein Purification
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- Mouse Anti-TNFRSF1B Recombinant Antibody (clone MR2-1) (MOR-0014-FY)
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- Species Reactivity: Human, Cynomolgus monkey, Rhesus monkey
- Type: Mouse IgG1
- Application: FC, FuncS, IA, IF, IP, WB
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- Mouse Anti-TNFRSF1B Recombinant Antibody (clone 80M2) (MOR-0018-FY)
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- Species Reactivity: Human, Rat
- Type: Mouse IgG1
- Application: FC, FuncS, IA, IF, IP
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- Mouse Anti-TNFRSF1B Recombinant Antibody (clone CBL430) (NEUT-2156CQ)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, ELISA, Neut
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- Mouse Anti-TNFRSF1B Recombinant Antibody (clone CBL431) (NEUT-2157CQ)
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- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: ICC, Neut
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- Mouse Anti-TNFRSF1B Recombinant Antibody (HPAB-0245-WJ) (HPAB-0245-WJ)
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- Species Reactivity: Human, Cynomolgus
- Type: Mouse IgG1
- Application: ELISA, FC
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- Mouse Anti-TNFRSF1B Recombinant Antibody; Fab Fragment (clone 32) (HPAB-1550WJ-F(E))
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- Derivation: Hybridoma
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, WB
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- Mouse Anti-TNFRSF1B Recombinant Antibody; scFv Fragment (clone 32) (HPAB-1550WJ-S(P))
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- Derivation: Hybridoma
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, WB
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- Scaffold Name: Kunitz domains
- Target: TNFR2
- Species Reactivity: Human
- Derivation: Phage display
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- Mouse Anti-TNFRSF1B Recombinant Antibody; scFv Fragment (HPAB-0245-WJ-S(P)) (HPAB-0245-WJ-S(P))
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- Species Reactivity: Human, Cynomolgus
- Type: Mouse scFv
- Application: ELISA, FC
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- Mouse Anti-TNFRSF1B Recombinant Antibody; Fab Fragment (HPAB-0245-WJ-F(E)) (HPAB-0245-WJ-F(E))
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- Species Reactivity: Human, Cynomolgus
- Type: Mouse Fab
- Application: ELISA, FC
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- Species Reactivity: Human, Cynomolgus
- Target: TNFRSF1B
- Host Animal: Mouse
- Application: ELISA, FC, Cell-uptake
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- Anti-TNFRSF1B Immunohistochemistry Kit (VS-0525-XY7381)
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- Species Reactivity: Human
- Target: TNFRSF1B
- Application: IHC
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For Research Use Only. Not For Clinical Use.
The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways.
Protein class
Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Human disease related genes, Plasma proteins
Predicted location
Membrane, Secreted (different isoforms)
Single cell type specificity
Cell type enhanced (Langerhans cells, dendritic cells, Macrophages, Kupffer cells, monocytes, T-cells)
Immune cell specificity
Immune cell enhanced (non-classical monocyte)
Cell line specificity
Cell line enhanced (CAPAN-2, K-562, THP-1, U-87 MG, U-937)
Interaction
Binds to TRAF2 (PubMed:8069916, PubMed:10206649). Interacts with BMX (PubMed:12370298). Interacts (activated form) with XPNPEP3 (PubMed:25609706).
Molecular function
Receptor
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