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TPX2
TPX2 (TPX2, Microtubule Nucleation Factor) is a Protein Coding gene. Diseases associated with TPX2 include Uterine Corpus Endometrial Carcinoma and Hepatocellular Carcinoma. Among its related pathways are Gene Expression and Regulation of TP53 Activity. Gene Ontology (GO) annotations related to this gene include GTP binding and protein kinase binding.
Protein class
Cancer-related genes
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Spermatocytes, Erythroid cells, Extravillous trophoblasts, Spermatogonia, Granulosa cells)
Immune cell specificity
Immune cell enhanced (T-reg)
Cell line specificity
Low cell line specificity
Interaction
Interacts with AURKA (PubMed:14580337, PubMed:18662907, PubMed:18663142). Interacts with importin-alpha; leading to inactivate TPX2 (PubMed:26165940). Interacts with HNRNPU; this interaction recruits HNRNPU to spindle microtubules (MTs) (PubMed:21242313, PubMed:25986610). Interacts with BCL2L10 (By similarity).
More Types Infomation
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: IHC-P, WB
- Mouse Anti-TPX2 Recombinant Antibody (VS3-WK1212) (VS3-WK1212)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB
- Mouse Anti-TPX2 Recombinant Antibody (VS3-WK1211) (VS3-WK1211)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IF
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- Derivation: Mouse
- Species Reactivity: Human, Mouse
- Type: Mouse IgG1
- Application: WB
-
- Derivation: Mouse
- Species Reactivity: Human, Mouse
- Type: Mouse IgG1
- Application: WB
-
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IHC-Fr, IHC-P, ICC, IF, IP
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For Research Use Only. Not For Clinical Use.