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WNT6

Anti-WNT6 Products
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB
- Anti-WNT6 Immunohistochemistry Kit (VS-0525-XY7937)
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- Species Reactivity: Human
- Target: WNT6
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Background
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is overexpressed in cervical cancer cell line and strongly coexpressed with another family member, WNT10A, in colorectal cancer cell line. The gene overexpression may play key roles in carcinogenesis. This gene and the WNT10A gene are clustered in the chromosome 2q35 region. The protein encoded by this gene is 97% identical to the mouse Wnt6 protein at the amino acid level.
Predicted location
Secreted
Single cell type specificity
Cell type enriched (Sertoli cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enriched (BEWO)
Interaction
Interacts with PORCN.
Molecular function
Developmental protein
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