Loading...
ATP6AP2
This gene encodes a protein that is associated with adenosine triphosphatases (ATPases). Proton-translocating ATPases have fundamental roles in energy conservation, secondary active transport, acidification of intracellular compartments, and cellular pH homeostasis. There are three classes of ATPases-F, P, and V. The vacuolar (V-type) ATPases have a transmembrane proton-conducting sector and an extramembrane catalytic sector. The encoded protein has been found associated with the transmembrane sector of the V-type ATPases.
Protein class
Disease related genes, Human disease related genes, Potential drug targets, Transporters
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (Hofbauer cells)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Interacts with renin (PubMed:12045255). Accessory component of the multisubunit proton-transporting vacuolar (V)-ATPase protein pump (PubMed:33065002). Interacts (via N-terminus) with ATP6AP1 (via N-terminus) (PubMed:29127204, PubMed:33065002). Interacts with ATP6V0D1; ATP6V0D1 is a V-ATPase complex subunit and the interaction promotes V-ATPase complex assembly (PubMed:33065002, PubMed:30374053). Interacts with TMEM9; TMEM9 is a V-ATPase assembly regulator and the interaction induces the interaction with ATP6V0D1 (PubMed:30374053). Interacts with VMA21 (via N-terminus); VMA21 is a V-ATPase accessory component (PubMed:29127204).
Molecular function
Receptor
More Types Infomation
Related Signaling Pathways
cAMP Signaling Pathway
Related Diseases
Morphine Addiction
- Mouse Anti-ATP6AP2 Recombinant Antibody (clone 48-8); Fab Fragment (HPAB-N0320-YC-F(E))
-
- Species Reactivity: Human, Mouse
- Type: Mouse Fab
- Application: WST-1 assay, Inhib
- Mouse Anti-ATP6AP2 Recombinant Antibody (clone 67-3); Fab Fragment (HPAB-N0319-YC-F(E))
-
- Species Reactivity: Human, Mouse
- Type: Mouse Fab
- Application: WST-1 assay, Inhib
- Mouse Anti-ATP6AP2 Recombinant Antibody (clone 48-8) (HPAB-N0320-YC)
-
- Species Reactivity: Human, Mouse
- Type: Mouse IgM
- Application: WST-1 assay, Inhib
- Mouse Anti-ATP6AP2 Recombinant Antibody (clone 67-3) (HPAB-N0319-YC)
-
- Species Reactivity: Human, Mouse
- Type: Mouse IgG2b
- Application: WST-1 assay, Inhib
- Mouse Anti-ATP6AP2 Recombinant Antibody (clone 48-8); scFv Fragment (HPAB-N0320-YC-S(P))
-
- Species Reactivity: Human, Mouse
- Type: Mouse scFv
- Application: WST-1 assay, Inhib
- Mouse Anti-ATP6AP2 Recombinant Antibody (clone 67-3); scFv Fragment (HPAB-N0319-YC-S(P))
-
- Species Reactivity: Human, Mouse
- Type: Mouse scFv
- Application: WST-1 assay, Inhib
Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us
Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag
For Research Use Only. Not For Clinical Use.