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ITGA6

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The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2/HER2 signaling. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]

Derivation:
Mouse
Species Reactivity:
Human
Type:
IgG
Application:
ELISA, WB, Dot, FuncS
Derivation:
Mouse
Species Reactivity:
Human
Type:
Fab
Application:
ELISA, IP, FuncS
Derivation:
Mouse
Species Reactivity:
Human
Type:
scFv
Application:
FC, WB, FuncS
Species Reactivity:
Human
Application:
FC, ICC/IF, IHC-Fr, IHC-P, IP
Species Reactivity:
Human, Mouse, Bovine
Type:
IgG2a
Application:
BL, IHC, CyTOF, FC
Derivation:
Phage display library screening
Species Reactivity:
Human
Type:
IgG
Application:
WB, IHC
Species Reactivity:
Human, Mouse, Dog
Type:
IgG
Application:
WB
Species Reactivity:
Human, Mouse, Rat
Type:
Rabbit IgG
Application:
WB, IHC
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