10-FnIII scaffold protein anti-Human IL-23
CAT#: SFN-L010
The tenth fibronectin type III domain (10Fn3) that bound IL-23 was isolated from the library using Phage display technology. The fibronectin type III domain (FN3) is a small autonomous folding unit which occurs in many animal proteins involving in ligand binding. The β-sandwich structure of FN3 closely resembles that of immunoglobulin domains. After affinity maturation, 10Fn3 variants were identified having affinities (KD=0.26 nM) for IL-23 as determined by biosensor technology. It's potential to be used in diagnostic, research and therapeutic applications.
Specifications
- Scaffold Name
- 10-FnIII
- Origin
- Fibronectin
- Core Structure
- β-sandwich of 7 β-strands
- Variable Regions
- 2–3 Loops
- Target
- IL-23
- Species Reactivity
- Human
- Expression Host
- E. coli
- Affinity Constant
- 0.26 nM
- Applications
- ELISA; immunohistochemistry; Microscopy; Flow Cytometer; Western Blotting; Functional Study
Target
- Alternative Names
- Fibronectin; 10-FnIII; IL23; IL-23
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for SFN-L010. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Related Diseases
Inflammatory Bowel Diseases
Rheumatoid Arthritis
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "IL23"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-419CL | Human Anti-IL23 Recombinant Antibody (TAB-419CL) | Inhib, FuncS | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-402CL | Afuco™ Anti-IL23 Recombinant Antibody (AFC-402CL), ADCC Enhanced | ELISA, WB | Human IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1332CQ | Mouse Anti-IL23 Recombinant Antibody (clone B-Z23) | Neut, ICC, IF | Mouse IgG1 |
| NEUT-1333CQ | Mouse Anti-IL23 Recombinant Antibody (clone MT155) | Neut | Mouse IgG2b |
| NEUT-1334CQ | Rat Anti-Il23 Recombinant Antibody (clone G23-8) | Neut, WB, FuncS, ELISA | Rat IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0274LY | Human Anti-IL23 Recombinant Antibody (HPAB-0274LY) | Inhib, ELISA | Humanized IgG1 |
| HPAB-0275LY | Human Anti-IL23 Recombinant Antibody (HPAB-0275LY) | Inhib, ELISA | Humanized IgG1 |
| HPAB-0262-FY | Human Anti-IL23 Recombinant Antibody (HPAB-0262-FY) | ELISA | Human IgG1 |
| HPAB-AP686-YC | Mouse Anti-IL23 Recombinant Antibody (clone 8C92H6) | ELISA | Mouse IgG |
| HPAB-AP687-YC | Human Anti-IL23 Recombinant Antibody (clone ch8C92H6) | ELISA | Chimeric (mouse/human) IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0417LY-S(P) | Mouse Anti-IL23 Recombinant Antibody; scFv Fragment (HPAB-0417LY-S(P)) | ELISA, Block | Mouse scfv |
| HPAB-AP686-YC-S(P) | Mouse Anti-IL23 Recombinant Antibody (clone 8C92H6); scFv Fragment | ELISA | Mouse scFv |
| HPAB-AP687-YC-S(P) | Human Anti-IL23 Recombinant Antibody (clone ch8C92H6); scFv Fragment | ELISA | Mouse scFv |
| HPAB-AP688-YC-S(P) | Human Anti-IL23 Recombinant Antibody (clone A24AM18); scFv Fragment | ELISA, Neut | Human scFv |
| HPAB-AP689-YC-S(P) | Human Anti-IL23 Recombinant Antibody (clone A5M20); scFv Fragment | ELISA, Neut | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0274LY-F(E) | Human Anti-IL23 Recombinant Antibody Fab Fragment (HPAB-0274LY-F(E)) | Inhib, ELISA | Humanized Fab |
| HPAB-0275LY-F(E) | Human Anti-IL23 Recombinant Antibody Fab Fragment (HPAB-0275LY-F(E)) | Inhib, ELISA | Humanized Fab |
| HPAB-0417LY-F(E) | Mouse Anti-IL23 Recombinant Antibody; Fab Fragment (HPAB-0417LY-F(E)) | ELISA, Block | Fab |
| HPAB-3397LY-F(E) | Human Anti-IL23 Recombinant Antibody (clone ABT-874); Fab Fragment | ELISA, FC, WB | Human Fab |
| HPAB-AP686-YC-F(E) | Mouse Anti-IL23 Recombinant Antibody (clone 8C92H6); Fab Fragment | ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY183 | Human Anti-IL23 (clone ABT-874) scFv-Fc Chimera | IA | Human IgG1, scFv-Fc |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: WB, FuncS, IF, Neut, ELISA, FC, IP
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
Application: Neut, ELISA, IF, IP, FuncS, FC, IHC
Application: FuncS, IF, Neut, ELISA, FC, IP, IHC
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: WB, IHC, ELISA, FC
Application: SPR, Inhib, FuncS
Application: ELISA, IHC, FC, IP, IF, BL
Application: FC, IHC, Cyt, FuncS
Application: Neut, ELISA, IF, IP, FuncS, FC
Application: ELISA, Neut, FuncS
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
