Recombinant Mouse Antibody (CNTO4088) is capable of binding to IL-23, expressed in Chinese Hamster Ovary cells (CHO).
Figure 1 Crystal structure analysis of anti-IL-23 antibody CNTO4088.
The X-ray structure of the Fab fragment revealed an unusual noncanonical conformation of CDR L1. Most antibodies with the kappa light chain exhibit a canonical structure for CDR L1 in which residue 29 anchors the CDR loop to the framework.
Teplyakov, A., Obmolova, G., Rogers, A., & Gilliland, G. L. (2010). Noncanonical conformation of CDR L1 in the anti-IL-23 antibody CNTO4088. Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 66(3), 229-232.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-419CL | Human Anti-IL23 Recombinant Antibody (TAB-419CL) | Inhib, FuncS | Human IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-402CL | Afuco™ Anti-IL23 Recombinant Antibody (AFC-402CL), ADCC Enhanced | ELISA, WB | Human IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
PABL-611 | Human Anti-IL23 Recombinant Antibody (clone CNTO1275) | Neut, ELISA | Humanized IgG |
HPAB-0262-FY | Human Anti-IL23 Recombinant Antibody (HPAB-0262-FY) | ELISA | Human IgG1 |
HPAB-AP686-YC | Mouse Anti-IL23 Recombinant Antibody (clone 8C92H6) | ELISA | Mouse IgG |
HPAB-AP687-YC | Human Anti-IL23 Recombinant Antibody (clone ch8C92H6) | ELISA | Chimeric (mouse/human) IgG |
HPAB-AP693-YC | Human Anti-IL23 Recombinant Antibody (clone A6M20) | ELISA | Humanized (mouse/human) IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
PSBL-606 | Human Anti-IL23 Recombinant Antibody (clone CNTO1275); scFv Fragment | Neut, ELISA | Humanized scFv |
PSBL-607 | Mouse Anti-IL23 Recombinant Antibody (clone CNTO4088); scFv Fragment | WB, FuncS | Mouse scFv |
HPAB-0274LY-S(P) | Human Anti-IL23 Recombinant Antibody (clone MAbQF20); scfv Fragment | Inhib, ELISA | Humanized scfv |
HPAB-0275LY-S(P) | Human Anti-IL23 Recombinant Antibody (clone MAbQF37); scfv Fragment | Inhib, ELISA | Humanized scfv |
HPAB-0417LY-S(P) | Mouse Anti-IL23 Recombinant Antibody; scFv Fragment (HPAB-0417LY-S(P)) | ELISA, Block | Mouse scfv |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-1332CQ | Mouse Anti-IL23 Recombinant Antibody (clone B-Z23) | Neut, ICC, IF | Mouse IgG1 |
NEUT-1333CQ | Mouse Anti-IL23 Recombinant Antibody (clone MT155) | Neut | Mouse IgG2b |
NEUT-1334CQ | Rat Anti-Il23 Recombinant Antibody (clone G23-8) | Neut, WB, FuncS, ELISA | Rat IgG1, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0274LY-F(E) | Human Anti-IL23 Recombinant Antibody (clone MAbQF20); Fab Fragment | Inhib, ELISA | Humanized Fab |
HPAB-0275LY-F(E) | Human Anti-IL23 Recombinant Antibody (clone MAbQF37); Fab Fragment | Inhib, ELISA | Humanized Fab |
HPAB-0417LY-F(E) | Mouse Anti-IL23 Recombinant Antibody; Fab Fragment (HPAB-0417LY-F(E)) | ELISA, Block | Fab |
HPAB-AP686-YC-F(E) | Mouse Anti-IL23 Recombinant Antibody (clone 8C92H6); Fab Fragment | ELISA | Mouse Fab |
HPAB-AP687-YC-F(E) | Human Anti-IL23 Recombinant Antibody (clone ch8C92H6); Fab Fragment | ELISA | Chimeric (mouse/human) Fab |
There are currently no Customer reviews or questions for PABL-612. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.