Mouse Anti-IL23 Recombinant Antibody (clone CNTO4088) (CAT#: PABL-612)
Recombinant Mouse Antibody (CNTO4088) is capable of binding to IL-23, expressed in Chinese Hamster Ovary cells (CHO).
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Figure 1 Crystal structure analysis of anti-IL-23 antibody CNTO4088.
The X-ray structure of the Fab fragment revealed an unusual noncanonical conformation of CDR L1. Most antibodies with the kappa light chain exhibit a canonical structure for CDR L1 in which residue 29 anchors the CDR loop to the framework.
Teplyakov, A., Obmolova, G., Rogers, A., & Gilliland, G. L. (2010). Noncanonical conformation of CDR L1 in the anti-IL-23 antibody CNTO4088. Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 66(3), 229-232.
Specifications
- Immunogen
- Human interleukin 23, alpha subunit p19
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human IL23
- Species Reactivity
- Human
- Clone
- CNTO4088
- Applications
- WB, FuncS
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- IL23A; interleukin 23, alpha subunit p19; P19; SGRF; IL-23; IL-23A; IL23P19; interleukin-23 subunit alpha; IL-23-A; IL-23p19; IL-23 subunit alpha; interleukin 23 p19 subunit; interleukin-23 subunit p19; JKA3 induced upon T-cell activation; interleukin-six, G-CSF related factor
- Gene ID
- 51561
- UniProt ID
- Q9NPF7
Related Resources
Inflammatory Bowel Diseases
Rheumatoid Arthritis
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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ScFv-Fc Chimera Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-419CL | Human Anti-IL23 Recombinant Antibody (TAB-419CL) | Inhib, FuncS | Human IgG |
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