Human Anti-IL23 (clone ABT-874) scFv-Fc Chimera (CAT#: VS-0325-FY183)
The anti-IL-23 scFv-Fc antibody targets Interleukin-23 (IL-23), a cytokine involved in immune regulation and inflammation. This antibody combines the specificity of the scFv with the Fc region's stability, offering a powerful tool for studying IL-23's role in autoimmune diseases and inflammatory processes, as well as potential therapeutic applications.
Specific Inquiry
Specifications
- Immunogen
- The recombinant human IL-12/IL-23 p40 subunit.
- Host Species
- Human
- Type
- Human IgG1, scFv-Fc
- Specificity
- Human IL23
- Species Reactivity
- Human
- Clone
- ABT-874
- Applications
- Immunoassay
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Target
- Alternative Names
- Human Interleukin-23; IL-23
- Long Name
- Human Interleukin-23
- Sequence Similarities
- Belongs to the type I cytokine receptor family. Type 2 subfamily.
- Cellular Localization
- Cell membrane
- Post Translation Modifications
- Phosphorylated in response to IL23.
Glycosylation at Asn262, Asn273, Asn29, Asn47, Asn81, Asn141, Asn180, and Asn232
Modification sites at PhosphoSitePlus
Glycosylation from GlyGen 9 sites
- Protein Refseq
- XP_011539092.1; XP_011539093.1; XP_047303183.1; XP_054190613.1; XP_054190614.1
- Function
- Human IL23 (Interleukin 23) is a cytokine involved in inflammatory responses, particularly in autoimmune diseases. It plays a role in T cell differentiation and is a target for therapeutic interventions in conditions like psoriasis and inflammatory bowel disease.
Recommended Products
Isotype Control
Secondary Antibody
Related Resources
Inflammatory Bowel Diseases
Rheumatoid Arthritis
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Human Antibody Products
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IgG Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-419CL | Human Anti-IL23 Recombinant Antibody (TAB-419CL) | Inhib, FuncS | Human IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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