Human Anti-IL23 (clone ABT-874) scFv-Fc Chimera
CAT#: VS-0325-FY183
The anti-IL-23 scFv-Fc antibody targets Interleukin-23 (IL-23), a cytokine involved in immune regulation and inflammation. This antibody combines the specificity of the scFv with the Fc region's stability, offering a powerful tool for studying IL-23's role in autoimmune diseases and inflammatory processes, as well as potential therapeutic applications.
Specifications
- Immunogen
- The recombinant human IL-12/IL-23 p40 subunit.
- Host Species
- Human
- Type
- Human IgG1, scFv-Fc
- Specificity
- Human IL23
- Species Reactivity
- Human
- Clone
- ABT-874
- Applications
- Immunoassay
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Target
- Alternative Names
- Human Interleukin-23; IL-23
- Long Name
- Human Interleukin-23
- Sequence Similarities
- Belongs to the type I cytokine receptor family. Type 2 subfamily.
- Cellular Localization
- Cell membrane
- Post Translation Modifications
- Phosphorylated in response to IL23.
Glycosylation at Asn262, Asn273, Asn29, Asn47, Asn81, Asn141, Asn180, and Asn232
Modification sites at PhosphoSitePlus
Glycosylation from GlyGen 9 sites
- Protein Refseq
- XP_011539092.1; XP_011539093.1; XP_047303183.1; XP_054190613.1; XP_054190614.1
- Function
- Human IL23 (Interleukin 23) is a cytokine involved in inflammatory responses, particularly in autoimmune diseases. It plays a role in T cell differentiation and is a target for therapeutic interventions in conditions like psoriasis and inflammatory bowel disease.
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Related Diseases
Inflammatory Bowel Diseases
Rheumatoid Arthritis
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "Clone ABT-874"
- CAT
- Product Name
See other products for "IL23"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-419CL | Human Anti-IL23 Recombinant Antibody (TAB-419CL) | Inhib, FuncS | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-402CL | Afuco™ Anti-IL23 Recombinant Antibody (AFC-402CL), ADCC Enhanced | ELISA, WB | Human IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1332CQ | Mouse Anti-IL23 Recombinant Antibody (clone B-Z23) | Neut, ICC, IF | Mouse IgG1 |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0417LY-S(P) | Mouse Anti-IL23 Recombinant Antibody; scFv Fragment (HPAB-0417LY-S(P)) | ELISA, Block | Mouse scfv |
| HPAB-0360-WJ-S(P) | Mouse Anti-IL23 Recombinant Antibody (clone m1A11); scFv Fragment | ELISA | Mouse scFv |
| HPAB-0361-WJ-S(P) | Mouse Anti-IL23 Recombinant Antibody (clone m11C1); scFv Fragment | ELISA | Mouse scFv |
| HPAB-0362-WJ-S(P) | Mouse Anti-IL23 Recombinant Antibody (clone m5F5); scFv Fragment | ELISA | Mouse scFv |
| HPAB-0363-WJ-S(P) | Mouse Anti-IL23 Recombinant Antibody (clone m21D1); scFv Fragment | ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0360-WJ | Mouse Anti-IL23 Recombinant Antibody (clone m1A11) | ELISA | Mouse IgG |
| HPAB-0361-WJ | Mouse Anti-IL23 Recombinant Antibody (clone m11C1) | ELISA | Mouse IgG |
| HPAB-0362-WJ | Mouse Anti-IL23 Recombinant Antibody (clone m5F5) | ELISA | Mouse IgG |
| HPAB-0363-WJ | Mouse Anti-IL23 Recombinant Antibody (clone m21D1) | ELISA | Mouse IgG |
| HPAB-0364-WJ | Mouse Anti-IL23 Recombinant Antibody (clone m13B8) | ELISA | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-AP686-YC-F(E) | Mouse Anti-IL23 Recombinant Antibody (clone 8C92H6); Fab Fragment | ELISA | Mouse Fab |
| HPAB-AP687-YC-F(E) | Human Anti-IL23 Recombinant Antibody (clone ch8C92H6); Fab Fragment | ELISA | Chimeric (mouse/human) Fab |
| HPAB-AP688-YC-F(E) | Human Anti-IL23 Recombinant Antibody (clone A24AM18); Fab Fragment | ELISA, Neut | Humanized (mouse/human) Fab |
| HPAB-AP689-YC-F(E) | Human Anti-IL23 Recombinant Antibody (clone A5M20); Fab Fragment | ELISA, Neut | Humanized (mouse/human) Fab |
| HPAB-AP690-YC-F(E) | Human Anti-IL23 Recombinant Antibody (clone A5M21); Fab Fragment | ELISA, Neut | Humanized (mouse/human) Fab |
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