A*0201/Human hTERT (ILAKFLHWL) MHC Tetramer

A*0201/Human hTERT (ILAKFLHWL) MHC Tetramer is available from Creative Biolabs.

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A*0201/Human hTERT (ILAKFLHWL) MHC Tetramer

A*0201/Human hTERT (ILAKFLHWL) MHC Tetramer (CAT#: MHC-LC792)

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of Telomerase-derived peptide of ILAKFLHWL sequence covering 540-548 and A*0201 molecule. The pMHC tetramer recognizes human CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.

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MSDS
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Datasheet

MSDS

Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number

Specifications

Allele
A*0201

Class
Class I

Antigen
hTERT

Antigen Species
Human

Peptide
ILAKFLHWL

Range
540-548

Application
FCM

Target

Antigen Introduction
Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, encoded by this gene, and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres. Deregulation of telomerase expression in somatic cells may be involved in oncogenesis. Studies in mouse suggest that telomerase also participates in chromosomal repair, since de novo synthesis of telomere repeats may occur at double-stranded breaks. Alternatively spliced variants encoding different isoforms of telomerase reverse transcriptase have been identified; the full-length sequence of some variants has not been determined. Alternative splicing at this locus is thought to be one mechanism of regulation of telomerase activity.

Alternative Names
TERT; telomerase reverse transcriptase; TP2; TRT; CMM9; EST2; TCS1; hTRT; DKCA2; DKCB4; hEST2; PFBMFT1; hTERT

Gene ID
7015

UniProt ID
O14746

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

See other products for "TERT"

For Research Use Only. Not For Clinical Use.

* Abbreviations

3D IHC3D Immunohistochemistry

ActivActivation

AgonistAgonist

ApopApoptosis

BABioassay

BIBioimaging

BlockBlocking

Cell ScreeningCell Screening

SeparationCell Separation

ChIPChromatin Immunoprecipitation

CMCDComplement Mediated Cell Depletion

CostimCostimulation

CytCytotoxicity

DepletionDepletion

DBDot Blot

EMElectron Microscopy

ELISAEnzyme-linked Immunosorbent Assay

ELISPOTEnzyme-linked Immunosorbent Spot

FCFlow Cytometry

FuncSFunctional Assay

GSGel Super Shift Assay

HAHemagglutination

IAImmunoassay

IBImmunoblotting

ICCImmunocytochemistry

IDImmunodiffusion

IFImmunofluorescence

IHCImmunohistochemistry

IHC-FrImmunohistochemistry-Frozen

IHC-PImmunohistochemistry-Paraffin

REImmunohistology - Resin Sections

IPImmunoprecipitation

IRMAImmunoradiometric Assay

SHIn situ hybridization

InhibInhibition

ICFCIntracellular Staining for Flow Cytometry

KO/KD-WBKnockout/Knockdown target confirmation by Western Blot

Live cell imagingLive cell imaging

CyTOF®Mass Cytometry

MeDIPMethylated DNA Immunoprecipitation

MultiplexMultiplex bead-based assay

NeutNeutralization

PPProtein Purification

PGProteogenomics

RIRadial Immunodiffusion

RIARadioimmunoassay

StimStimulation

SPRSurface Plasmon Resonance

TCTissue Culture

TBTurbidimetry

WBWestern Blot

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