Anti-Human ABCA1 Recombinant Antibody (ABCA1-4/18)
CAT#: TAB-0632CLV
The anti-ABCA1 antibody capable of binding to ATP-binding cassette transporter A1 which is essential for the assembly of nascent HDL particles by phospholipid and apolipoprotein. The specific antibody can be used in the detection of native ABCA1 polypeptide.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm & vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/57283/if_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: nuclear Neuronal cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/69889/151525_B_7_5.jpg
Normal Tissue
Figure 3 Lung
Macrophages Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/69889/151525_A_1_4.jpg
Normal Tissue
Figure 4 Colon
Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/69889/151525_A_9_3.jpg
Normal Tissue
Figure 5 Liver
Hepatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/69889/151525_A_7_4.jpg
Normal Tissue
Figure 6 Kidney
Cells in glomeruli Staining: Low Intensity: Weak Quantity: 75%-25% Location: nuclear Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/69889/151525_A_8_5.jpg
Normal Tissue
Figure 7 Testis
Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/69889/151525_A_6_6.jpg
Normal Tissue
Figure 8 Lymph node
Germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/69889/151525_A_7_8.jpg
RNA Expression
Figure 9 RNA cell line category: Cell line enhanced (HSkMC, U-87 MG)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000165029-ABCA1
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Specifications
- Immunogen
- Human ABCA1 extracellular domain
- Host Species
- Mouse
- Specificity
- Human
- Clone
- ABCA1-4/18
- Related Disease
- Familial hypoalphalipoproteinemia (FHA)
Target
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Easily Integrates into Workflow
We experienced smooth integration into our existing workflow. The ease of use and consistency has streamlined our research processes significantly.
Specialized Application Success
We needed an antibody for a specialized application, and this one performed excellently. The results were clear, and it opened new avenues for our research projects.
Responsive to Protocol Adjustments
Adjusted protocols to suit different experimental needs without detracting from the antibody's performance. This flexibility is a big plus for our dynamic research demands.
Q&As
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How can I dispose of unused or expired antibodies?
A: Dispose of according to your institution's guidelines for biohazardous waste. Typically, this involves placing the antibody in a designated biohazard container for proper disposal.
-
What safety precautions are recommended when handling antibodies?
A: Wear appropriate PPE, including gloves and lab coat. Handle materials under a biosafety cabinet if required and follow your institution's safety guidelines for biological reagents.
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How do I minimize proteolytic degradation of my samples?
A: Use protease inhibitors in your lysis buffer to protect against proteolytic degradation. Keep samples on ice and process them quickly to minimize degradation.
View the frequently asked questions answered by Creative Biolabs Support.
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Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "Clone ABCA1-4/18"
- CAT
- Product Name
See other products for "ABCA1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-4000z | Mouse Anti-ABCA1 Recombinant Antibody (clone 40C6) | WB, FC, ICC, IF, IHC | Mouse IgG2b, κ |
| MRO-1624-CN | Rabbit Anti-ABCA1 Polyclonal Antibody (MRO-1624-CN) | WB, IF, IHC, FC | Rabbit IgG |
| VS3-XY1 | Mouse Anti-ABCA1 Recombinant Antibody (clone 4G2) | WB, IP, IF, IHC | Mouse IgG1 |
| VS7-HM8 | Mouse Anti-ABCA1 Recombinant Antibody (clone 6B7A11) | ICC, FCM | Mouse IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0008 | Hi-Affi™ Rabbit Anti-ABCA1 Recombinant Antibody (clone DS8AB) | WB, ICC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC321 | Recombinant Anti-ABCA1 Vesicular Antibody, EV Displayed (VS-0425-YC321) | ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY11 | Anti-ABCA1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY12 | Anti-Mouse ABCA1 Immunohistochemistry Kit | IHC |
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