Anti-Human ADAM12 Recombinant Antibody Fab Fragment (7B8) (CAT#: TAB-0665CLV-F(E))
The anti-ADAM12 antibody target A Disintegrin And Metal loprotease12 which is highly upregulated in a variety of human cancers including breast, bladder, laryngeal and lung carcinomas.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30867/380_A6_3_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30867/380_A6_3_selected.jpg
Figure 2 Testis
(Cells in seminiferous ducts Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30866/156493_A_6_6.jpg
(Cells in seminiferous ducts Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30866/156493_A_6_6.jpg
Figure 3 High expression in placenta
(Decidual cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Syncytiotrophoblasts - cell body Staining: High Intensity: Strong Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30866/156493_A_2_7.jpg
(Decidual cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Syncytiotrophoblasts - cell body Staining: High Intensity: Strong Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30866/156493_A_2_7.jpg
Figure 4 Colon
(Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30866/156493_A_8_3.jpg
(Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30866/156493_A_8_3.jpg
Figure 5 RNA cell line category: Cell line enhanced.
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000148848-ADAM12
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000148848-ADAM12
Specifications
- Immunogen
- full-length ADAM 12-S
- Host Species
- Mouse
- Specificity
- Human
- Clone
- 7B8
- Related Disease
- Breast cancer, bladder cancer, laryngeal cancer, lung carcinomas
Target
- Alternative Names
- ADAM12; ADAM metallopeptidase domain 12; MCMP; MLTN; CAR10; MLTNA; MCMPMltna; ADAM12-OT1; disintegrin and metalloproteinase domain-containing protein 12; meltrin-alpha; metalloprotease-disintegrin 12 transmembrane
- Gene ID
- 8038
- UniProt ID
- U5NE98
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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Antibody Magnetic Beads
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0665CLV | Anti-Human ADAM12 Recombinant Antibody (7B8) | IF |
Customer Reviews and Q&As
Customer Review
Q&As
Well Worth the Investment
Though initially skeptical about the cost, the performance of this antibody has proven it well worth the investment.
High-Quality Product
I found this antibody to be of high quality. The binding efficiency was great, and it worked well across various assays.
Consistent Performance
I have been using this antibody for months and have always had consistent performance. A reliable antibody for sure.
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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