Anti-Human ADAM12 Recombinant Antibody Fab Fragment (7B8) (CAT#: TAB-0665CLV-F(E))
The anti-ADAM12 antibody target A Disintegrin And Metal loprotease12 which is highly upregulated in a variety of human cancers including breast, bladder, laryngeal and lung carcinomas.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30867/380_A6_3_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30867/380_A6_3_selected.jpg
Figure 2 Testis
(Cells in seminiferous ducts Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30866/156493_A_6_6.jpg
(Cells in seminiferous ducts Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30866/156493_A_6_6.jpg
Figure 3 High expression in placenta
(Decidual cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Syncytiotrophoblasts - cell body Staining: High Intensity: Strong Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30866/156493_A_2_7.jpg
(Decidual cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Syncytiotrophoblasts - cell body Staining: High Intensity: Strong Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30866/156493_A_2_7.jpg
Figure 4 Colon
(Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30866/156493_A_8_3.jpg
(Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30866/156493_A_8_3.jpg
Figure 5 RNA cell line category: Cell line enhanced.
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000148848-ADAM12
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000148848-ADAM12
Specifications
- Immunogen
- full-length ADAM 12-S
- Host Species
- Mouse
- Specificity
- Human
- Clone
- 7B8
- Related Disease
- Breast cancer, bladder cancer, laryngeal cancer, lung carcinomas
Target
- Alternative Names
- ADAM12; ADAM metallopeptidase domain 12; MCMP; MLTN; CAR10; MLTNA; MCMPMltna; ADAM12-OT1; disintegrin and metalloproteinase domain-containing protein 12; meltrin-alpha; metalloprotease-disintegrin 12 transmembrane
- Gene ID
- 8038
- UniProt ID
- U5NE98
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0665CLV | Anti-Human ADAM12 Recombinant Antibody (7B8) | IF |
Customer Reviews and Q&As
Customer Review
Q&As
Well Worth the Investment
Though initially skeptical about the cost, the performance of this antibody has proven it well worth the investment.
High-Quality Product
I found this antibody to be of high quality. The binding efficiency was great, and it worked well across various assays.
Consistent Performance
I have been using this antibody for months and have always had consistent performance. A reliable antibody for sure.
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