Mouse Anti-ADAM12 Recombinant Antibody (clone F1196-113-1) (CAT#: VS-0524-YC17)
The product is an anti-meltrin α antibody clone F1196-113-1. It was confirmed that the antibody has an inhibitory activity for the meltrin α protease activity.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30867/380_A6_3_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30867/380_A6_3_selected.jpg
Figure 2 Testis
(Cells in seminiferous ducts Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30866/156493_A_6_6.jpg
(Cells in seminiferous ducts Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30866/156493_A_6_6.jpg
Figure 3 High expression in placenta
(Decidual cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Syncytiotrophoblasts - cell body Staining: High Intensity: Strong Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30866/156493_A_2_7.jpg
(Decidual cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Syncytiotrophoblasts - cell body Staining: High Intensity: Strong Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30866/156493_A_2_7.jpg
Figure 4 Colon
(Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30866/156493_A_8_3.jpg
(Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30866/156493_A_8_3.jpg
Figure 5 RNA cell line category: Cell line enhanced.
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000148848-ADAM12
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000148848-ADAM12
Specifications
- Immunogen
- Purified human meltrin α-FLAG
- Host Species
- Mouse
- Derivation
- Hybridoma
- Type
- Mouse IgG
- Specificity
- Human Meltrin α
- Species Reactivity
- Human
- Clone
- F1196-113-1
- Applications
- ELISA, Inhib, Antagonist
Product Property
- Purification
- Protein G purified
- Purity
- >95%
- Buffer
- PBS, pH 7.4
- Preservative
- No preservative
- Storage
- Centrifuge briefly prior to opening vial. Store at 4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- ADAM Metallopeptidase Domain 12; Meltrin-Alpha; MLTN; Disintegrin And Metalloproteinase Domain-Containing Protein 12; A Disintegrin And Metalloproteinase Domain 12 (Meltrin Alpha); Metalloprotease-Disintegrin 12 Transmembrane; Meltrin Alpha; EC 3.4.24.58; EC 3.4.24.-;
- Gene ID
- 8038
- UniProt ID
- O43184
- Long Name
- Meltrin-alpha
- Cellular Localization
- Cell membrane; Single-pass type I membrane protein (Isoform 1); Secreted (Isoform 2-4)
- Post Translation Modifications
- Glycosylation at Asn111, Asn149, Asn381, Asn452, and Asn651
- Protein Refseq
- XP_016872195.1; XP_024303978.1; XP_054222811.1; XP_054222812.1; XP_054222813.1
- Function
- Involved in skeletal muscle regeneration, specifically at the onset of cell fusion.
Recommended Products
Secondary Antibody
Isotype Control
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0665CLV | Anti-Human ADAM12 Recombinant Antibody (7B8) | IF |
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