Anti-CCNT1 Intrabody [+36GFP] (IAB-B032(G))
Recombinant anti-CCNT1 intrabody in fusion with +36GFP works within cells to bind human CCNT1, expressed in 293T cells. Anti-hCyclinT1 intrabodies can be designed to block HIV-1 replication without causing cellular toxicity, and as a result, they may be useful agents for "intracellular immunization"-based gene therapy strategies for HIV-1 infection/AIDS.
Specifications
- Immunogen
- human cyclin T1
- Host
- human
- Type
- scFv-(+36GFP)
- Cell Penetrating Peptide
- +36 GFP
GFP with a theoretical net charge of +36 (+36 GFP) penetrated several different mammalian cell lines at very low (nanomolar) concentrations. Cationic peptides and proteins have been observed to penetrate cells, and both natural and synthetic cell-penetrating peptides are widely used as delivery vehicles. However, whereas a covalent link between the cell-penetrating peptide and its cargo is typically required.
- Species Reactivity
- human
- Applications
- Products can be used for: Fluorescence-activated cell sorting; Immunocytochemistry; Functional studies
Target
- Alternative Names
- CCNT1; cyclin T1; CCNT; CYCT1; HIVE1; cyclin-T1; cyclin C-related protein; CDK9-associated C-type protein
- Entrez Gene ID
- 904
- UniProt ID
- O60563
For lab research use only, not for diagnostic, therapeutic or any in vivo human use.
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