Anti-Human CD34 Recombinant Antibody Fab Fragment (h4C8) (CAT#: TAB-149LC-F(E))
TAB-149LC is a recombinant humanized antibody, which targets CD34. It has a strong affinity for highly-expressed CD34 on human myeloid leukemia cells. By attaching it to magnetic nano materials, it can be used to create immunomagnetic beads for sorting marrow hemopoietic stem cells. This antibody has the ability to significantly reduce the incidence of HAMA, making clinical hematopoietic stem cell transplantation safer. It is primarily used in the treatment of specific malignant blood diseases and solid tumors. TAB-149LC-F(E) antibody is the Fab fragment antibody form of TAB-149LC antibody. Fab fragments, the antigen-binding domains of an antibody molecule, consist of two amino acid chains composed of VH+CH1 and VL+CL domains.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line HUVEC TERT2 shows localization to nucleoplasm & cell junctions.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/36723/1751_G1_7_cr57fd220c70be0_selected.jpg
(Immunofluorescent staining of human cell line HUVEC TERT2 shows localization to nucleoplasm & cell junctions.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/36723/1751_G1_7_cr57fd220c70be0_selected.jpg
Figure 2 Cerebral cortex
(Endothelial cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18/155469_B_8_5.jpg
(Endothelial cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18/155469_B_8_5.jpg
Figure 3 Colon
(Endothelial cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18/155469_A_9_3.jpg
(Endothelial cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18/155469_A_9_3.jpg
Figure 4 Kidney
(Cells in glomeruli
Staining: High
Intensity: Strong
Quantity: 75%-25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18/155469_A_8_5.jpg
(Cells in glomeruli
Staining: High
Intensity: Strong
Quantity: 75%-25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18/155469_A_8_5.jpg
Figure 5 RNA cell line category: Group enriched (HUVEC TERT2, MOLT-4)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000174059-CD34
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000174059-CD34
Specifications
- Host Species
- Human
- Derivation
- Humanized
- Type
- Humanized antibody
- Specificity
- Human
- Clone
- h4C8
- Applications
- ELISA
- Related Disease
- Malignant blood diseasesm, Solid tumors
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Flow Cytometry (FC) related Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-175-F(E) | Recombinant Human Anti-human CD34 Antibody Fab Fragment | Neut, IF, FuncS | Fab |
| HPAB-M0472-YC-F(E) | Mouse Anti-CD34 Recombinant Antibody; Fab Fragment (HPAB-M0472-YC-F(E)) | WB, IF, IHC, IP, WB | Mouse Fab |
| HPAB-1042-FY-S(P) | Human Anti-CD34 Recombinant Antibody (clone c4C8); Fab Fragment | ELISA | Chimeric (mouse/human) Fab |
| HPAB-1043-FY-S(P) | Human Anti-CD34 Recombinant Antibody (clone C5B12); Fab Fragment | ELISA | Chimeric (mouse/human) Fab |
| HPAB-1044-FY-S(P) | Human Anti-CD34 Recombinant Antibody (clone C2e10); Fab Fragment | ELISA | Chimeric (mouse/human) Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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