Creative Biolabs Recombinant Antibodies
Products
  1. Home
  2. CD72
  3. Anti-CD72 immunotoxin J3-109 (IgG)-PAP

Anti-CD72 immunotoxin J3-109 (IgG)-PAP (AGTO-G083P)

This immunotoxin was achieved by conjugating/fusing the Anti-CD72 monoclonal antibody to Pokeweed antiviral protein. It was expressed in CHO and purified with affinity chromatography. The immunotoxin selectively binds to tumor cells and the toxin enters cells by receptor-mediated endocytosis. Then PAP is introduced into the cytoplasm where it eventually causes cell death by inactivating ribosomes. It was designed for treatment of acute lymphoblastic leukemias (ALL).      
  • Datasheet

Specifications
Host
Mouse
Species Reactivity
Human
Clone
J3-109
Molecule Class
IgG-PAP
Toxin Description
Pokeweed antiviral protein (PAP) is a type I ribosome inactivating protein isolated from the pokeweed plant, Phytolacca americana. The toxin is introduced into the cytoplasm where it eventually causes cell death by inactivating ribosomes.
Applications
This product is suitable for use in cytotoxicity assay, functional assay and immunotherapy.
Related Disease
Acute lymphoblastic leukemias (ALL)
Target
Alternative Names
CD72; CD72 molecule; LYB2; CD72b; B-cell differentiation antigen CD72; lyb-2; CD72 antigen; Pokeweed Antiviral Protein
Entrez Gene ID
971
UniProt ID
P21854

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

See other products for "CD72"
Recombinant Human Anti-CD72 Antibody (sc02-004)    ( HPAB-0062CQ )
Hi-Affi™ Recombinant Rabbit Anti-CD72 Monoclonal Antibody (DS578AB)    ( MOR-0578 )
Recombinant Mouse Anti-Human CD72 Antibody    ( MOB-1916z )
Recombinant Mouse Anti-Human CD72 Antibody (clone 4G4)    ( MOB-1640MZ )
Anti-CD72 (clone 10D6.8.1)-SPP-DM1 ADC    ( ADC-177LZY )
Recombinant Human Anti-CD72 Antibody    ( CBMAB-0273MC )
Recombinant Human Anti-CD72 Antibody (sc02-025)    ( HPAB-0063CQ )
Recombinant Human Anti-CD72 Antibody Fab Fragment (sc02-004)    ( HPAB-0062CQ-F(E) )
>> MORE
Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us
Send Inquiry Now!
Name:
* Phone:
* E-mail Address:
* Service & Products Interested:
Project Description:
* Verification Code:
Please input "biolabs"(case insensitive) as verification code.
Contact Us to Order
Tel: 1-631-381-2994
Fax: 1-631-207-8356
Email:

Increase Efficiency to Accelerate Your Research & Discovery Process

Increase Efficiency to Accelerate Your Research & Discovery Process

Creative Biolabs is the leading custom service provider that has extensive experience in various antibody production and engineering fields. Our service portfolio includes mouse and rat monoclonal antibody production ...

Find out more >

USA

45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-381-2994
Fax: 1-631-207-8356

Europe

Tel: 44-207-097-1828
Email:
Follow us on:
           

Terms of Service-Privacy Policy     © 2007 - 2019 Creative-Biolabs All Rights Reserved