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CD72

Anti-CD72 Recombinant Antibody Products

    • Target: CD72
    • Linker: SPP (N-succinimidyl-4-(2-pyridyldithio)pentanoate)
    • Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
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    • Target: CD72
    • Linker: MCC (Maleimidomethyl cyclohexane-1-carboxylate)
    • Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
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For Research Use Only. Not For Clinical Use.


Plays a role in B-cell proliferation and differentiation
Protein class

CD markers

Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Cell type enhanced (B-cells, Kupffer cells, Macrophages, NK-cells, Hofbauer cells, dendritic cells)

Immune cell specificity

Group enriched (naive B-cell, memory B-cell)

Cell line specificity

Cell line enhanced (Daudi, Karpas-707, REH, U-698)

Interaction

Homodimer; disulfide-linked. Associates with CD5. Interacts (tyrosine phosphorylated) with PTPN6/SHP-1 (By similarity).

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