Human Anti-CD72 Recombinant Antibody (clone sc02-004); Fab Fragment
CAT#: HPAB-0062CQ-F(E)
This recombinant human Fab fragment specifically binds to CD72. 004 antibody does internalise upon binding to the CD72 antigen. It can be used in the treatment of B cell associated disorders.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line SH-SY5Y
Immunofluorescent staining of human cell line SH-SY5Y shows localization to nucleoplasm & mitochondria.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/44658/1373_H2_4_selected.jpg
Normal Tissue
Figure 2 Spleen
High expression
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2505/ihc_selected.jpg
Normal Tissue
Figure 3 Bone marrow
Hematopoietic cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2505/6524_B_5_4.jpg
Normal Tissue
Figure 4 High expression in lymph node
Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2505/6524_A_9_8.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enhanced (Daudi, Karpas-707, REH, U-698)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000137101-CD72
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Specifications
- Host Species
- Human
- Derivation
- Phage display library
- Type
- Human Fab
- Specificity
- Human CD72
- Species Reactivity
- Human
- Clone
- sc02-004
- Applications
- IHC
- Related Disease
- B cell associated disorders
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
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Thorough instructions
The product's extensive instructions have proven to be highly helpful in ensuring proper usage and maximizing its effectiveness.
Dependable performance
This product has consistently produced outstanding results with every batch, which is crucial for our long-term projects.
Provided with thorough protocols
The antibody was given comprehensive instructions that were very helpful in guiding our research. They made sure we got the greatest outcomes by checking several applications and doing troubleshooting.
Q&As
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When employing the antibody in research, are there any specifics to be mindful of?
A: Yes, rigorous adherence to protocols, avoid cross-contamination, and maintain appropriate storage conditions are necessary to ensure accurate and repeatable findings.
-
Is the antibody suitable for treating animals?
A: You may use part of the antibody in veterinary settings, but you must use formulations that have been specifically designed and tested for use with animals.
-
What sets humanized antibodies apart from chimeric ones?
A: While humanized antibodies are mostly composed of human tissue with the exception of non-human species' antigen-binding regions, chimeric antibodies incorporate larger portions of both human and non-human origins.
View the frequently asked questions answered by Creative Biolabs Support.
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Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "Clone sc02-004"
- CAT
- Product Name
See other products for "CD72"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-G083P | Anti-CD72 immunotoxin J3-109 (IgG)-PAP | Cytotoxicity assay, Function study |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0273MC | Human Anti-CD72 Recombinant Antibody (clone YC015) | ELISA, WB, FuncS | |
| MOB-0274MC | Human Anti-CD72 Recombinant Antibody (clone YC016); scFv Fragment | ELISA, WB, FuncS | Human scFv |
| HPAB-0062CQ | Human Anti-CD72 Recombinant Antibody (clone sc02-004) | IHC | Human IgG1, κ |
| HPAB-0063CQ | Human Anti-CD72 Recombinant Antibody (clone sc02-025) | IHC | Human IgG1, λ |
| FAMAB-1080CQ | Human Anti-CD72 Recombinant Antibody (clone BU40) | WB, FC, Apop | Human IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0578 | Hi-Affi™ Rabbit Anti-CD72 Recombinant Antibody (clone DS578AB) | ICC, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0062CQ-S(P) | Human Anti-CD72 Recombinant Antibody (clone sc02-004); scFv Fragment | IHC | Human scFv |
| HPAB-0063CQ-S(P) | Human Anti-CD72 Recombinant Antibody (clone sc02-025); scFv Fragment | IHC | Human scFv |
| HPAB-2053-FY-S(P) | Human Anti-CD72 Recombinant Antibody (clone II-2); scFv Fragment | FC | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0063CQ-F(E) | Human Anti-CD72 Recombinant Antibody (clone sc02-025); Fab fragment | IHC | Human Fab |
| HPAB-2053-FY-F(E) | Human Anti-CD72 Recombinant Antibody (clone II-2); Fab Fragment | FC | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC506 | Recombinant Anti-CD72 Vesicular Antibody, EV Displayed (VS-0425-YC506) | ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1216 | Anti-CD72 Immunohistochemistry Kit | IHC |
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