Afuco™ Anti-Human CDH2 ADCC Recombinant Antibody, ADCC Enhanced (CAT#: AFC-144CL)
Anti-CDH2 ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. This is a fully human antibody against N-Cadherin for therapeutic and diagnostic methods in cancer.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane & cell junctions.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/141/if_selected.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane & cell junctions.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/141/if_selected.jpg
Figure 2 Cerebral cortex
(Neuropil
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/58574/142431_B_7_5.jpg
(Neuropil
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/58574/142431_B_7_5.jpg
Figure 3 Colon
(Peripheral nerve/ganglion
Staining: High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/58574/142431_A_7_3.jpg
(Peripheral nerve/ganglion
Staining: High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/58574/142431_A_7_3.jpg
Figure 4 Liver
(Cholangiocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Hepatocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/58574/142431_A_8_4.jpg
(Cholangiocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Hepatocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/58574/142431_A_8_4.jpg
Figure 5 Kidney
(Bowman's capsule
Staining: High
Intensity: Strong
Quantity:>75%
Proximal tubules (cell body)
Staining: High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/58574/142431_A_8_5.jpg
(Bowman's capsule
Staining: High
Intensity: Strong
Quantity:>75%
Proximal tubules (cell body)
Staining: High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/58574/142431_A_8_5.jpg
Figure 6 Testis
(Sertoli cells
Staining: High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/58574/142431_A_6_6.jpg
(Sertoli cells
Staining: High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/58574/142431_A_6_6.jpg
Figure 7 Heart muscle
(Cardiomyocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/58574/142431_B_5_6.jpg
(Cardiomyocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/58574/142431_B_5_6.jpg
Figure 8 RNA cell line category: Cell line enhanced (AF22, BJ, fHDF/TERT166)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000170558-CDH2
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000170558-CDH2
Specifications
- Host Species
- Human
- Derivation
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Cancer
Product Property
- Purity
- >95% as determined by analysis by RP-HPLC
- Storage
- Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C.
Target
- Alternative Names
- CDH2; cadherin 2, type 1, N-cadherin (neuronal); cadherin 2; cadherin-2; CDHN; NCAD; CD325; CDw32
- Gene ID
- 1000
- UniProt ID
- P19022
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-188 | Recombinant Anti-human CDH2 Antibody | ELISA, WB, FC, FuncS | IgG |
| MOB-0332MZ | Recombinant Mouse Anti-Human CDH2 Antibody (clone 7H12) | IHC | Mouse antibody |
| MRO-1059-CN | Rabbit Anti-CDH2 Recombinant Antibody (clone CBACN-393) | WB, IF, IHC, FC | Rabbit IgG |
| MOB-0140F | Mouse Anti-CDH2 Recombinant Antibody (MOB-0140F) | IHC-P, IF | Mouse IgG |
| MOB-0141F | Mouse Anti-CDH2 Recombinant Antibody (MOB-0141F) | IHC-P, IF | Mouse IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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