Anti-DNA Antibody-Cytokine Fusion Protein, IgG-IL2 (CAT#: ACFP-SH062)
This antibody-cytokine fusion protein was achieved by conjugating/fusing the Anti-DNA IgG to IL2. It was expressed in CHO and purified with affinity chromatography. The immunocytokine retains the ability to bind the DNA as well as the biological activity of IL2. The IL2 can specifically reach tumor parts, and can be used for reversing the local immunosuppression state of tumors and activating part bodies and integral antitumor immunity. This immunocytokine was designed for treating melanoma or lung cancer or other solid tumors.
Specific Inquiry
Specifications
- Target
- DNA
- Molecule Class
- L Kappa; IgG1-IL2
- Species Reactivity
- Human
- Expression Host
- CHO
- Clone
- TNT
- Related Disease
- Melanoma or lung cancer or other solid tumors
- Cytokine 1
- IL2
- Cytokines 1 Description
- Interleukin-2 (IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system. It is a protein that regulates the activities of white blood cells (leukocytes, often lymphocytes) that are responsible for immunity. IL-2 is part of the body's natural response to microbial infection, and in discriminating between foreign ("non-self") and "self". IL-2 mediates its effects by binding to IL-2 receptors, which are expressed by lymphocytes.
- Cytokine 1 Species
- Human
- Applications
- This product can be used therapeutically to deliver biologically active ligands to a desired tissue.
Target
- Alternative Names
- Deoxyribonucleic acid; ss DNA
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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