Anti-Human DSC2 Recombinant Antibody scFv Fragment (332) (CAT#: TAB-255MZ-S(P))
This antibody that binds to human DSC2 can be potentially used for treating various cancers including lung, colon, pancreatic, prostate, breast, gastric or liver cancers. It may be also used as an active ingredient for damaging DSC2-expressing cells via the effector function.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12615/200_G3_2_selected.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12615/200_G3_2_selected.jpg
Figure 2 Esophagus
(Squamous epithelial cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12615/28214_B_5_1.jpg
(Squamous epithelial cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12615/28214_B_5_1.jpg
Figure 3 Colon
(Glandular cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12615/28214_A_7_3.jpg
(Glandular cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12615/28214_A_7_3.jpg
Figure 4 RNA cell line category: Cell line enhanced (BEWO, CAPAN-2, HaCaT, hTCEpi, OE19, SK-BR-3, SuSa)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000134755-DSC2
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000134755-DSC2
Specifications
- Host Species
- Human
- Derivation
- Phage library
- Type
- Human antibody
- Specificity
- Human
- Clone
- 332
- Applications
- ADCC assay
- Related Disease
- Cancers such as lung, colon, pancreatic, prostate, breast, gastric or liver cancers
Target
- Alternative Names
- DSC2; desmocollin 2; DG2; DSC3; CDHF2; ARVD11; DGII/III; desmocollin-2; cadherin family member 2; desmosomal glycoprotein II/III
- Gene ID
- 1824
- UniProt ID
- Q02487
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibody Products
Fab Antibody Products
ScFv Antibody Products
Human Antibody Products
Rabbit Monoclonal Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-291 | Recombinant Anti-human DSC2 Antibody | ELISA, WB, Dot, FuncS | IgG |
| MHH-291 | Recombinant Human Anti-human DSC2 Antibody | ELISA, FacS, FuncS | IgG |
| MOB-1094MZ | Recombinant Mouse Anti-Human DSC2 Antibody (clone 1F2) | ELISA | Mouse antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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