Recombinant Human Anti-human DSC2 Antibody (CAT#: MHH-291)
Recombinant Human Antibody coresponds to Human DSC2, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-DSC2 mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-DSC2 mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12615/200_G3_2_selected.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12615/200_G3_2_selected.jpg
Figure 2 Esophagus
(Squamous epithelial cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12615/28214_B_5_1.jpg
(Squamous epithelial cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12615/28214_B_5_1.jpg
Figure 3 Colon
(Glandular cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12615/28214_A_7_3.jpg
(Glandular cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12615/28214_A_7_3.jpg
Figure 4 RNA cell line category: Cell line enhanced (BEWO, CAPAN-2, HaCaT, hTCEpi, OE19, SK-BR-3, SuSa)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000134755-DSC2
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000134755-DSC2
Specifications
- Immunogen
- Human desmocollin 2
- Host Species
- Human
- Derivation
- Human
- Type
- IgG
- Specificity
- Tested positive against native Human desmocollin 2
- Species Reactivity
- Human
- Applications
- Antibody assay: Enzyme-linked Immunosorbent Assay; Fluorescence activated Cell Sorting; Functional Study
Product Property
- Purity
- Purity>95% by SDS-PAGE
- Storage
- Store at -20°C. Open under aseptic conditions.
Target
- Alternative Names
- DSC2; desmocollin 2; DG2; DSC3; CDHF2; ARVD11; DGII/III; desmocollin-2; cadherin family member 2; desmosomal glycoprotein II/III
- Gene ID
- 1824
- UniProt ID
- Q02487
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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See other products for "DSC2"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-291 | Recombinant Anti-human DSC2 Antibody | ELISA, WB, Dot, FuncS | IgG |
| MOB-1094MZ | Recombinant Mouse Anti-Human DSC2 Antibody (clone 1F2) | ELISA | Mouse antibody |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-291-F(E) | Recombinant Anti-human DSC2 Antibody Fab Fragment | IF, Neut, FuncS | Fab |
| MHH-291-F(E) | Recombinant Human Anti-human DSC2 Antibody Fab Fragment | FC, WB, FuncS | Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-291-S(P) | Recombinant Anti-human DSC2 Antibody scFv Fragment | ELISA, WB, FC, FuncS | scFv |
| MHH-291-S(P) | Recombinant Human Anti-human DSC2 Antibody scFv Fragment | ELISA, WB, IP, FuncS | scFv |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-255MZ | Anti-Human DSC2 Recombinant Antibody (332) | Cyt | Human antibody |
| TAB-255MZ-S(P) | Anti-Human DSC2 Recombinant Antibody scFv Fragment (332) | ADCC assay | Human antibody |
| TAB-256MZ-S(P) | Anti-Human DSC2 Recombinant Antibody scFv Fragment (545) | ADCC assay | Human antibody |
| TAB-255MZ-F(E) | Anti-Human DSC2 Recombinant Antibody Fab Fragment (332) | ADCC assay | Human antibody |
| TAB-256MZ-F(E) | Anti-Human DSC2 Recombinant Antibody Fab Fragment (545) | ADCC assay | Human antibody |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4144 | Hi-Affi™ Rabbit Anti-DSC2 Recombinant Antibody (clone SI219DS) | ELISA | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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