Anti-Mouse Emb Recombinant Antibody (3E64) (CAT#: TAB-330MZ)
This antibody 3E64 showing cytotoxicity or a cytotoxicity inducing activity provides a potentially agent for the prophylaxis or therapy of autoimmune diseases or allergic diseases.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
FC
Figure 1 is a figure shows evaluation of a binding activity of an anti-Embigin antibody to mouse Embigin expressing rat cells and rat cells by flow cytometry.
Isotype (rat IgG) relative to the anti-Embigin antibody was 5 μg/mL concentration, and a culture supernatant was used as the anti-Embigin antibody (anti-emb antibody).
FuncS
Figure 2 is a figure shows evaluation of cell depletion specificity of a toxin-modified anti-Embigin antibody in pathogenic cells.
FuncS
Figure 3 is a figure shows evaluation of the clinical score of a multiple sclerosis model by transferring cells after selectively depleting Th17 cells with an anti-Embigin antibody into a mouse.
FuncS
Figure 4 is a figure shows evaluation of an efficacy, on clinical score, of administration of, before onset of pathology, an anti-Embigin antibody to a mouse induced to make a multiple sclerosis model by immunizing with PLP.
PLP was mixed with Freund's complete adjuvant and subcutaneously immunized once. The anti-Embigin antibody (300 μg) was administered twice on days 7 and 14 (shown by arrows) after immunization. The clinical score was evaluated until day 18 after PLP immunization.
Specifications
- Immunogen
- Mouse Embigin overexpressing cells
- Host Species
- Rat
- Specificity
- Mouse
- Clone
- 3E64
- Applications
- FC, FuncS
- Related Disease
- Multiple sclerosis, psoriasis, rheumatism, chronic noninfectious uveitis, and glomerulonephritis
Applications
- Application Notes
- This antibody has been reported for use in Flow Cytotoxicityometry, Functional Assay.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Single Domain Antibody Products
IgG Antibody Products
Mouse Antibody Products
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-850-VHH | Recombinant Anti-Human EMB VHH Single Domain Antibody | ICC, ChiP, FC, FA | Llama VHH |
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For Research Use Only. Not For Clinical Use.
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