Anti-Mouse Emb Recombinant Antibody (3E64) (CAT#: TAB-330MZ)

This antibody 3E64 showing cytotoxicity or a cytotoxicity inducing activity provides a potentially agent for the prophylaxis or therapy of autoimmune diseases or allergic diseases.


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FC

Figure 1 is a figure shows evaluation of a binding activity of an anti-Embigin antibody to mouse Embigin expressing rat cells and rat cells by flow cytometry.

Figure 1 is a figure shows evaluation of a binding activity of an anti-Embigin antibody to mouse Embigin expressing rat cells and rat cells by flow cytometry.

Isotype (rat IgG) relative to the anti-Embigin antibody was 5 μg/mL concentration, and a culture supernatant was used as the anti-Embigin antibody (anti-emb antibody).

FuncS

Figure 2 is a figure shows evaluation of cell depletion specificity of a toxin-modified anti-Embigin antibody in pathogenic cells.

Figure 2 is a figure shows evaluation of cell depletion specificity of a toxin-modified anti-Embigin antibody in pathogenic cells.

FuncS

Figure 3 is a figure shows evaluation of the clinical score of a multiple sclerosis model by transferring cells after selectively depleting Th17 cells with an anti-Embigin antibody into a mouse.

Figure 3 is a figure shows evaluation of the clinical score of a multiple sclerosis model by transferring cells after selectively depleting Th17 cells with an anti-Embigin antibody into a mouse.

FuncS

Figure 4 is a figure shows evaluation of an efficacy, on clinical score, of administration of, before onset of pathology, an anti-Embigin antibody to a mouse induced to make a multiple sclerosis model by immunizing with PLP.

Figure 4 is a figure shows evaluation of an efficacy, on clinical score, of administration of, before onset of pathology, an anti-Embigin antibody to a mouse induced to make a multiple sclerosis model by immunizing with PLP.

PLP was mixed with Freund's complete adjuvant and subcutaneously immunized once. The anti-Embigin antibody (300 μg) was administered twice on days 7 and 14 (shown by arrows) after immunization. The clinical score was evaluated until day 18 after PLP immunization.


Specifications

  • Immunogen
  • Mouse Embigin overexpressing cells
  • Host Species
  • Rat
  • Specificity
  • Mouse
  • Clone
  • 3E64
  • Applications
  • FC, FuncS
  • Related Disease
  • Multiple sclerosis, psoriasis, rheumatism, chronic noninfectious uveitis, and glomerulonephritis

Applications

  • Application Notes
  • This antibody has been reported for use in Flow Cytotoxicityometry, Functional Assay.

Target

  • Alternative Names
  • Gp70; AL022799

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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See other products for "Clone 3E64"

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Single-domain Antibody

CAT Product Name Application Type
NAB-850-VHH Recombinant Anti-Human EMB VHH Single Domain Antibody ICC, ChiP, FC, FA Llama VHH

Recombinant Antibody

CAT Product Name Application Type
MOB-0227MC Rabbit Anti-EMB Recombinant Antibody (clone FQS22) FC, IP, WB

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-1143 Hi-Affi™ Rabbit Anti-EMB Recombinant Antibody (clone DS1143AB) WB Rabbit IgG

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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