Afuco™ Anti-Human F12 ADCC Recombinant Antibody, ADCC Enhanced

CAT#: AFC-242CL

Anti-F12 ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. The anti-factor XII/FXIIa antibodies provides thrombo protection in extracorporeal circulation without increasing bleeding risk.

Gene Expression
Figure 1 RNA cell line category: Cell line enhanced (HDLM-2, MCF7, PC-3, SH-SY5Y, U-937)

Specifications

  • Host Species
  • Human
  • Derivation
  • Human
  • Type
  • ADCC enhanced antibody
  • Species Reactivity
  • Human
  • Related Disease
  • Thromboembolism

Product Property

  • Purity
  • >98% by SDS-PAGE and HPLC analysis
  • Storage
  • 4°C or -20°C, avoid repeated freezing and thawing.

Target

  • Alternative Names
  • F12; coagulation factor XII (Hageman factor); HAF; HAE3; HAEX; coagulation factor XII; Hageman factor; beta-factor XIIa part 1; beta-factor XIIa part 2; coagulation factor XIIa heavy chain; coagulation factor XIIa light chain
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Detailed Documentation
The accompanying documentation is thorough and provides all required information for optimal use. Very user-friendly.
Breast cancer biomarkers at key points during disease progression
Exceptional Purity
The purity of this antibody is exceptional. Minimal background staining has enhanced our imaging results significantly.
Breast cancer biomarkers at key points during disease progression
Works in Various Systems
We've successfully used this antibody across different systems, including mammalian cell lines and primary cells.

Q&As

  1. How can I optimize the blocking step in my protocols?

    A: Employ suitable inhibitors (such as BSA or non-fat milk) and adjust concentration and time to reduce non-specific binding while keeping the target antigen visible.

  2. What methods are available for conjugating the antibody with detection agents?

    A: In chemical conjugation, substances such as maleimides or NHS esters are used. For several conjugation procedures, commercial kits and manufacturer protocols are available.

  3. How should I troubleshoot low or inconsistent signals in my assays?

    A: Examine and refine each step: detection techniques, antibody dilutions, incubation periods, and sample preparation. Verify the expiration dates and reagent integrity.

View the frequently asked questions answered by Creative Biolabs Support.

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Downloadable Resources

Download resources about recombinant antibody development and antibody engineering to boost your research.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

MSDS

COA

Certificate of Analysis Lookup

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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