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  • Afuco™ Anti-Human F2RL1 ADCC Recombinant Antibody, ADCC Enhanced

Afuco™ Anti-Human F2RL1 ADCC Recombinant Antibody, ADCC Enhanced (CAT#: AFC-245CL)

Anti-F2RL1 ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. The anti-PAR-2 antibodies can be used for treatment of pain, including post-operative incision pain, neuropathic pain, fracture pain, osteroporotic fracture pain, bone cancer pain or gout joint pain; inflammatory pain associated with irritable bowel syndrome; and inflammation related to rheumatoid arthritis or osteoarthritis.

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Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/14091/1740_E4_17_cr57fce65847914_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Figure 2 Cerebral cortex
(Glial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12989/33496_B_8_5.jpg
Figure 3 Stomach
Figure 3 Stomach
(Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12989/33496_A_5_1.jpg
Figure 4 Colon
Figure 4 Colon
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12989/33496_A_8_3.jpg
Figure 5 Liver
Figure 5 Liver
(Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12989/33496_A_8_4.jpg
Figure 6 Kidney
Figure 6 Kidney
(Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12989/33496_A_9_5.jpg
Figure 7 Testis
Figure 7 Testis
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12989/33496_A_6_6.jpg
Figure 8 Lymph node
Figure 8 Lymph node
(Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12989/33496_A_9_8.jpg
RNA Expression
Figure 9 RNA cell line category: Cell line enhanced (PC-3, RPTEC TERT1)
Figure 9 RNA cell line category: Cell line enhanced (PC-3, RPTEC TERT1)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000164251-F2RL1

Specifications

  • Host Species
  • Human
  • Derivation
  • Human
  • Type
  • ADCC enhanced antibody
  • Species Reactivity
  • Human
  • Related Disease
  • Inflammatory Diseases

Product Property

  • Purity
  • 90–95% (SDS-PAGE)
  • Storage
  • Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • F2RL1; coagulation factor II (thrombin) receptor-like 1; PAR2; GPR11; proteinase-activated receptor 2; thrombin receptor-like 1; G-protein coupled receptor 11; protease-activated receptor 2; coagulation factor II receptor-like 1

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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See other products for "F2RL1"

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Human Antibody Products Mouse Antibody Products IgG Antibody Products ScFv Antibody Products Fab Antibody Products ScFv-Fc Chimera Products
CAT Product Name Application Type
TAB-0934CL Human Anti-F2RL1 Recombinant Antibody (TAB-0934CL) ELISA, RIA, FC Human IgG, κ
TAB-0935CL Human Anti-F2RL1 Recombinant Antibody (TAB-0935CL) ELISA, RIA, FC Human IgG, κ
TAB-0934CL-S(P) Human Anti-F2RL1 Recombinant Antibody; scFv Fragment (TAB-0934CL-S(P)) ELISA, RIA, FC Human scFv
TAB-0935CL-S(P) Human Anti-F2RL1 Recombinant Antibody; scFv Fragment (TAB-0935CL-S(P)) ELISA, RIA, FC Human scFv
TAB-0934CL-F(E) Human Anti-F2RL1 Recombinant Antibody; Fab Fragment (TAB-0934CL-F(E)) ELISA, RIA, FC Human Fab

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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