Afuco™ Anti-Human FASLG ADCC Recombinant Antibody, ADCC Enhanced (CAT#: AFC-249CL)
Anti-FASLG ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. The humanized antibodies directed against human Fas ligands (also named CD95L or Apo1L and hereinafter abbreviated as FasL) for the prevention and/or treatment of skin diseases associated with keratinocytes acantholysis, particularly for the prevention and/or treatment of pemphigus.
Specific Inquiry
Normal Tissue
Figure 1 IHC staining of human lymph node
(Immunohistochemical staining of human lymph node shows distinct cytoplasmic positivity in subsets of cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/54959/ihc_selected.jpg
(Immunohistochemical staining of human lymph node shows distinct cytoplasmic positivity in subsets of cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/54959/ihc_selected.jpg
Figure 2 Cerebral cortex
(Neuronal cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/54959/134178_B_8_5.jpg
(Neuronal cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/54959/134178_B_8_5.jpg
Figure 3 Kidney
(Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/54959/134178_A_8_5.jpg
(Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/54959/134178_A_8_5.jpg
Figure 4 Testis
(Cells in seminiferous ducts Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/54959/134178_A_6_6.jpg
(Cells in seminiferous ducts Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/54959/134178_A_6_6.jpg
Figure 5 Bone marrow
(Hematopoietic cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/54959/134178_B_5_4.jpg
(Hematopoietic cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/54959/134178_B_5_4.jpg
Figure 6 Lymph node
(Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/54959/134178_A_8_8.jpg
(Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/54959/134178_A_8_8.jpg
Specifications
- Host Species
- Humanized
- Derivation
- Humanized
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Skin Diseases
Product Property
- Purity
- >95% (SDS-PAGE)
- Storage
- Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C.
Target
- Alternative Names
- FASLG; Fas ligand (TNF superfamily, member 6); APTL; FASL; CD178; CD95L; ALPS1B; CD95-L; TNFSF6; APT1LG1; tumor necrosis factor ligand superfamily member 6; CD95 ligand; fas antigen ligand; apoptosis antigen ligand; apoptosis (APO-1) antigen ligand 1
- Gene ID
- 356
- UniProt ID
- P48023
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "FASLG"
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-025WM | Human Anti-FASLG Recombinant Antibody (TAB-025WM) | ELISA | Humanized Antibody |
| TAB-025WM-S(P) | Human Anti-FASLG Recombinant Antibody; scFv Fragment (TAB-025WM-S(P)) | ELISA | Humanized scFv |
| TAB-025WM-F(E) | Human Anti-FASLG Recombinant Antibody; Fab Fragment (TAB-025WM-F(E)) | ELISA | Humanized Fab |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-026WM | Rabbit Anti-FASLG Recombinant Antibody (TAB-026WM) | ELISA, IHC | Rabbit IgG |
| TAB-026WM-S(P) | Rabbit Anti-FASLG Recombinant Antibody; scFv Fragment (TAB-026WM-S(P)) | ELISA, IHC | Rabbit scFv |
| TAB-026WM-F(E) | Rabbit Anti-FASLG Recombinant Antibody; Fab Fragment (TAB-026WM-F(E)) | ELISA, IHC | Rabbit Fab |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-027WM | Anti-Human FASLG Recombinant Antibody (E09) | ELISA | Human Antibody |
| TAB-028WM | Anti-Human FASLG Recombinant Antibody (3E1) | FC | Human Antibody |
| TAB-027WM-S(P) | Anti-Human FASLG Recombinant Antibody scFv Fragment (E09) | ELISA | Human Antibody |
| TAB-027WM-F(E) | Anti-Human FASLG Recombinant Antibody Fab Fragment (E09) | ELISA | Human Antibody |
| TAB-028WM-F(E) | Anti-Human FASLG Recombinant Antibody Fab Fragment (3E1) | FC | Human Antibody |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0703CT | Recombinant Mouse anti-Human FASLG Monoclonal antibody (Bmg2.3) | FC, IP | |
| HPAB-0127-YC | Mouse Anti-FASLG Recombinant Antibody (clone mF919) | ELISA, FC | Mouse IgG |
| HPAB-0128-YC | Human Anti-FASLG Recombinant Antibody (clone Hu F919) | ELISA, FC | Humanized IgG |
| HPAB-2823LY | Human Anti-FASLG Recombinant Antibody (HPAB-2823LY) | ELISA | Human IgG |
| HPAB-2825LY | Human Anti-FASLG Recombinant Antibody (HPAB-2825LY) | ELISA | Human IgG |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-777CQ | Mouse Anti-FASLG Recombinant Antibody (clone NOK-1) | FC, FuncS, Neut | Mouse IgG1, κ |
| NEUT-778CQ | Hamster Anti-FASLG Recombinant Antibody (clone 4H9) | ELISA, FC, Neut | Hamster IgG |
| NEUT-780CQ | Mouse Anti-FASLG Recombinant Antibody (clone CBL675) | ELISA, Neut | Mouse IgG2b |
| NEUT-781CQ | Mouse Anti-FASLG Recombinant Antibody (clone CBL256) | FC, IHC, Neut | Mouse IgG1 |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-779CQ | Mouse Anti-FASLG Recombinant Antibody (clone B-R17) | Block | Mouse IgG1 |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0127-YC-S(P) | Mouse Anti-FASLG Recombinant Antibody (clone mF919); scFv Fragment | ELISA, FC | Mouse scFv |
| HPAB-0179CQ-S(P) | Human Anti-FASLG Recombinant Antibody (clone 4G11); scFv Fragment | ELISA, FC, Neut | Human scFv |
| HPAB-2823LY-S(P) | Human Anti-FASLG Recombinant Antibody; scFv Fragment (HPAB-2823LY-S(P)) | ELISA | Human scFv |
| HPAB-2824LY-S(P) | Human Anti-FASLG Recombinant Antibody; scFv Fragment (HPAB-2824LY-S(P)) | ELISA | Human scFv |
| HPAB-2825LY-S(P) | Human Anti-FASLG Recombinant Antibody; scFv Fragment (HPAB-2825LY-S(P)) | ELISA | Human scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0127-YC-F(E) | Mouse Anti-FASLG Recombinant Antibody (clone mF919); Fab Fragment | ELISA, FC | Mouse Fab |
| HPAB-0179CQ-F(E) | Human Anti-FASLG Recombinant Antibody (clone 4G11); Fab Fragment | ELISA, FC, Neut | Human Fab |
| HPAB-2823LY-F(E) | Human Anti-FASLG Recombinant Antibody; Fab Fragment (HPAB-2823LY-F(E)) | ELISA | Human Fab |
| HPAB-2824LY-F(E) | Human Anti-FASLG Recombinant Antibody; Fab Fragment (HPAB-2824LY-F(E)) | ELISA | Human Fab |
| HPAB-2825LY-F(E) | Human Anti-FASLG Recombinant Antibody; Fab Fragment (HPAB-2825LY-F(E)) | ELISA | Human Fab |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for AFC-249CL. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.