Recombinant Anti-human FRMD4A Intrabody [(D-Arg)9] (CAT#: IAB-B059(A))

Recombinant anti-FRMD4A intrabody linked to (D-Arg)9 works within cells to direct against human FRMD4A, expressed in CHO cells. The intrabody can be used in therapeutic methods for treating proliferative disorders, including squamous cell carcinoma (SCC).


Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Fc Engineering:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
Normal Tissue
RNA Expression

Specifications

  • Immunogen
  • human FERM domain containing 4A
  • Host Species
  • human
  • Type
  • scFv-(D-Arg)9
  • Cell Penetrating Peptide
  • (D-Arg)9
    It has been proven that polyarginine peptides composed of nine arginine amino acids (Arg-9) are able to translocate across cells very efficiently. This raises the question if molecular dynamics simulations would show a similar pathway for this highly hydrophilic and charged peptide as predicted for the Tat peptide. The simplicity of Arg-9 over other CPPs also helps isolate the role of the Arg sidechain on the translocation without the effect of other sidechains. Therefore, in this work we study computationally the translocation of Arg-9 through a lipid bilayer and show that the translocation mechanism is the same as for the Tat peptide.
  • Species Reactivity
  • human
  • Applications
  • Formats of immunological tests: Coimmunopricipation; Functional studies

Product Property

  • Purity
  • 90–95% (SDS-PAGE)
  • Storage
  • Short Term Storage: 4°C
    Long Term Storage: -20°C

Target

  • Alternative Names
  • FRMD4A; FERM domain containing 4A; FRMD4; bA295P9.4; FERM domain-containing protein 4A; FERM domain containing 4

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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See other products for "FRMD4A"

Intrabody

CAT Product Name Application Type
IAB-B059(G) Recombinant Anti-human FRMD4A Intrabody [+36 GFP] ELISA, IF, Neut, FuncS scFv-(+36GFP)
IAB-B059(T) Recombinant Anti-human FRMD4A Intrabody [Tat] FC, IF, FuncS scFv-Tat

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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