Afuco™ Anti-Human FZD2 ADCC Recombinant Antibody, ADCC Enhanced
CAT#: AFC-283CL
Anti-FZD2 ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. The antibody specifically bind Fzd2, and may promote internalization of the Fzd2 receptor by the cancer cells and/or prevent ligand binding to Fzd2. It is used for treatment of specific cancers such as late stage hepatocellular carcinoma.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line CACO-2
Immunofluorescent staining of human cell line CACO-2 shows localization to nucleoplasm, nuclear bodies & cell junctions.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/57667/1240_D11_7_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IHC staining of human heart muscle
Immunohistochemical staining of human heart muscle shows moderate cytoplasmic positivity in myocytes.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/57667/ihc_selected.jpg
Subcellular Location and Protein Expression
Figure 3 IF staining of human cell line A549
Immunofluorescent staining of human cell line A549 shows localization to nucleoplasm & nuclear bodies.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/57667/991_A9_8_red_green.jpg
Subcellular Location and Protein Expression
Figure 4 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & nuclear bodies.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/57667/983_A9_1_red_green.jpg
Normal Tissue
Figure 5 Colon
Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Glandular cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/57667/131007_A_9_3.jpg
Normal Tissue
Figure 6 Liver
Hepatocytes
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/57667/131007_A_7_4.jpg
Normal Tissue
Figure 7 Kidney
Cells in tubules
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/57667/131007_A_8_5.jpg
Normal Tissue
Figure 8 Testis
Cells in seminiferous ducts
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/57667/131007_A_6_6.jpg
Normal Tissue
Figure 9 Heart muscle
Cardiomyocytes
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/57667/131007_B_5_6.jpg
Normal Tissue
Figure 10 Lymph node
Non-germinal center cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/57667/131007_A_8_8.jpg
RNA Expression
Figure 11 RNA cell line category: Cell line enhanced (BJ hTERT+ SV40 Large T+)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000180340-FZD2
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Specifications
- Host Species
- Humanized
- Derivation
- Humanized
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Cancer
Product Property
- Purity
- >98% by SDS-PAGE and HPLC analysis
- Storage
- 4 °C, -20°C if preferred
Target
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "Fzd2"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-1042-VHH | Recombinant Anti-Human Fzd2 VHH Single Domain Antibody | WB, IP, ChiP, Neut, ELISA | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2608z | Mouse Anti-FZD2 Recombinant Antibody (clone 9G6) | ELISA, WB | Mouse IgG2b, κ |
| MOB-0748CT | Recombinant Mouse anti-Human FZD2 Monoclonal antibody (EML2217) | ELISA, WB |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0386CL | Anti-Human GAD2 Recombinant Antibody | ELISA, WB | Human antibody |
| TAB-0386CL-S(P) | Anti-Human FZD2 Recombinant Antibody scFv Fragment | ELISA, WB | Human antibody |
| TAB-0386CL-F(E) | Anti-Human FZD2 Recombinant Antibody Fab Fragment | ELISA, WB | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC342 | Recombinant Anti-FZD2 Vesicular Antibody, EV Displayed (VS-0425-YC342) | ELISA, FC, Cell-uptake |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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