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    Anti-Human FZD2 Recombinant Antibody (CAT#: TAB-296CL)

    Recombinant Humanized monoclonal antibody expressed in CHO binding to Human FZD2. The antibody specifically bind Fzd2, and may promote internalization of the Fzd2 receptor by the cancer cells and/or prevent ligand binding to Fzd2. It is used for treatment of specific cancers such as late stage hepatocellular carcinoma.

    Specific Inquiry
    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    • Formats:

    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
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    Purity :
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    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location and Protein Expression
    Figure 1 IF staining of human cell line CACO-2
    Figure 1 IF staining of human cell line CACO-2
    (Immunofluorescent staining of human cell line CACO-2 shows localization to nucleoplasm, nuclear bodies & cell junctions.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/57667/1240_D11_7_selected.jpg
    Figure 2 IHC staining of human heart muscle
    Figure 2 IHC staining of human heart muscle
    (Immunohistochemical staining of human heart muscle shows moderate cytoplasmic positivity in myocytes.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/57667/ihc_selected.jpg
    Figure 3 IF staining of human cell line A549
    Figure 3 IF staining of human cell line A549
    (Immunofluorescent staining of human cell line A549 shows localization to nucleoplasm & nuclear bodies.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/57667/991_A9_8_red_green.jpg
    Figure 4 IF staining of human cell line U-2 OS
    Figure 4 IF staining of human cell line U-2 OS
    (Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & nuclear bodies.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/57667/983_A9_1_red_green.jpg
    Normal Tissue
    Figure 5 Colon
    Figure 5 Colon
    (Endothelial cells
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Glandular cells
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/57667/131007_A_9_3.jpg
    Figure 6 Liver
    Figure 6 Liver
    (Hepatocytes
    Staining:Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/57667/131007_A_7_4.jpg
    Figure 7 Kidney
    Figure 7 Kidney
    (Cells in tubules
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/57667/131007_A_8_5.jpg
    Figure 8 Testis
    Figure 8 Testis
    (Cells in seminiferous ducts
    Staining:Medium
    Intensity: Strong
    Quantity: <25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/57667/131007_A_6_6.jpg
    Figure 9 Heart muscle
    Figure 9 Heart muscle
    (Cardiomyocytes
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/57667/131007_B_5_6.jpg
    Figure 10 Lymph node
    Figure 10 Lymph node
    (Non-germinal center cells
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/57667/131007_A_8_8.jpg
    RNA Expression
    Figure 11 RNA cell line category: Cell line enhanced (BJ hTERT+ SV40 Large T+)
    Figure 11 RNA cell line category: Cell line enhanced (BJ hTERT+ SV40 Large T+)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000180340-FZD2

    Specifications

    • Derivation
    • Humanized
    • Type
    • Antibody
    • Species Reactivity
    • Human
    • Related Disease
    • Cancer

    Product Property

    • Purity
    • >98% by SDS-PAGE and HPLC analysis
    • Storage
    • 4 °C, -20°C if preferred

    Target

    • Alternative Names
    • FZD2; frizzled class receptor 2; Fz2; fz-2; fzE2; hFz2; frizzled-2; frizzled homolog 2; frizzled family receptor 2; frizzled 2, seven transmembrane spanning receptor

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

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    Single Domain Antibody Products IgG Antibody Products Human Antibody Products Extracellular Vesicle (EV) Antibody Products
    CAT Product Name Application Type
    NAB-1042-VHH Recombinant Anti-Human Fzd2 VHH Single Domain Antibody WB, IP, ChiP, Neut, ELISA Llama VHH

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    For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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