Afuco™ Anti-Human GCG ADCC Recombinant Antibody, ADCC Enhanced (CAT#: AFC-289CL)
Anti-GCG ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. The monoclonal antibodies that bind to glucagon are useful in immunoassays of glucagon levels, and/or in vivo, ex vivo or in vitro immunochemical and other imaging methods for detecting glucagon levels, and for diagnostic, prognostic and predictive purposes, and for optimizing therapeutic regimens in patients in which glucagon signaling is implicated in pathogenesis.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to endoplasmic reticulum.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/36760/1675_C6_32_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to endoplasmic reticulum.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/36760/1675_C6_32_selected.jpg
Figure 2 High expression in pancreas
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/36760/123313_A_2_3_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/36760/123313_A_2_3_val_selected.jpg
Figure 3 Low expression in liver
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/36760/123313_A_9_4_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/36760/123313_A_9_4_val_selected.jpg
Figure 4 Pancreas
(Pancreatic endocrine cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/40/255_A_2_3.jpg
(Pancreatic endocrine cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/40/255_A_2_3.jpg
Figure 5 RNA cell line category: Cell line enhanced (EFO-21, U-2 OS, U-698)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000115263-GCG
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000115263-GCG
Specifications
- Host Species
- Human
- Derivation
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Diabetes Type 2
Product Property
- Purity
- Purity>95% by SDS-PAGE
- Storage
- Store at -20°C. Open under aseptic conditions.
Target
- Alternative Names
- GCG; glucagon; GLP1; GLP2; GRPP; preproglucagon; glucagon-like peptide 1; glucagon-like peptide 2; glicentin-related polypeptide
- Gene ID
- 2641
- UniProt ID
- P01275
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0117MZ | Recombinant Mouse Anti-Glucagon-Like Peptide (GLP1) Antibody (clone JD/GLP-3/20) | ICC, IHC-P | Mouse antibody |
| VS3-CJ252 | Mouse Anti-GCG Recombinant Antibody (VS3-CJ252) | IHC | Mouse IgG2b |
| VS3-CJ253 | Mouse Anti-GCG Recombinant Antibody (VS3-CJ253) | IHC | Mouse IgG1 |
| VS3-XY3366 | Rabbit Anti-GCG Recombinant Antibody (clone R04-8D3) | WB, IHC-P, ICC, IF | Rabbit IgG |
| VS7-HM999 | Mouse Anti-GCG Recombinant Antibody (clone CBL317HM) | WB, ELISA | Mouse IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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