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GCG

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The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon.

Derivation:
Human
Species Reactivity:
Human
Type:
ADCC enhanced antibody
Protein Chemical Formula:
C165H249N49O51S1
Protein Average Weight:
3767.1 Da
CAS Number:
16941-32-5
Derivation:
Phage display library screening
Species Reactivity:
Human
Type:
IgG
Application:
WB
Species Reactivity:
Human
Type:
IgG2
Application:
ELISA
Species Reactivity:
Human
Type:
Fab
Application:
ELISA
Species Reactivity:
Human
Type:
scFv
Application:
ELISA
Species Reactivity:
Human
Type:
Human IgG4
Application:
ELISA, FC, RIA
Species Reactivity:
Human
Type:
Human IgG4
Application:
ELISA, FC, RIA
Species Reactivity:
Human
Type:
Human IgG1
Application:
ELISA, FC, RIA
Species Reactivity:
Human
Type:
Human scFv
Application:
ELISA, FC, RIA
Species Reactivity:
Human
Type:
Human scFv
Application:
ELISA, FC, RIA
Species Reactivity:
Human
Type:
Human scFv
Application:
ELISA, FC, RIA
Species Reactivity:
Human
Type:
Human Fab
Application:
ELISA, FC, RIA
Species Reactivity:
Human
Type:
Human Fab
Application:
ELISA, FC, RIA
Species Reactivity:
Human
Type:
Human Fab
Application:
ELISA, FC, RIA
Derivation:
Human
Species Reactivity:
Human
Type:
Antibody
Species Reactivity:
Human
Type:
Mouse antibody
Application:
ICC, IHC-P
Species Reactivity:
Human, Mouse
Type:
IgG
Application:
WB
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