Recombinant Anti-HIV Vif Intrabody [+36 GFP] (CAT#: IAB-B036(G))

Recombinant anti-HIV Vif intrabody in fusion with +36GFP works within cells and is directed against HIV Vif, expressed in CHO cells. This intrabody efficiently bound Vif protein and neutralized its infectivity-enhancing function. Intrabody-expressing cells were shown to be highly refractory to challenge with different strains of HIV-1 and HIV-1-infected cells.


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Specifications

  • Immunogen
  • Human immunodeficiency virus type 1 (HIV-1)-encoded Vif protein
  • Host Species
  • rabbit
  • Type
  • scFv-(+36GFP)
  • Cell Penetrating Peptide
  • +36 GFP
    GFP with a theoretical net charge of +36 (+36 GFP) penetrated several different mammalian cell lines at very low (nanomolar) concentrations. Cationic peptides and proteins have been observed to penetrate cells, and both natural and synthetic cell-penetrating peptides are widely used as delivery vehicles. However, whereas a covalent link between the cell-penetrating peptide and its cargo is typically required.
  • Species Reactivity
  • HIV
  • Applications
  • Used for immunoassay techniques such as: Protein fragment complementation; Neutralization; Functional studies

Product Property

  • Purity
  • 95% by HPLC
  • Storage
  • Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • HIV vif; SOR protein; Virion infectivity factor

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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