Recombinant Anti-HIV Vif Intrabody [(D-Arg)9] (CAT#: IAB-B036(A))
Recombinant anti-HIV Vif intrabody linked to (D-Arg)9 works within cells to bind HIV Vif, expressed in CHO cells. This intrabody efficiently bound Vif protein and neutralized its infectivity-enhancing function. Intrabody-expressing cells were shown to be highly refractory to challenge with different strains of HIV-1 and HIV-1-infected cells.
Specific Inquiry
Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Specifications
- Immunogen
- Human immunodeficiency virus type 1 (HIV-1)-encoded Vif protein
- Host Species
- rabbit
- Type
- scFv-(D-Arg)9
- Cell Penetrating Peptide
- (D-Arg)9
It has been proven that polyarginine peptides composed of nine arginine amino acids (Arg-9) are able to translocate across cells very efficiently. This raises the question if molecular dynamics simulations would show a similar pathway for this highly hydrophilic and charged peptide as predicted for the Tat peptide. The simplicity of Arg-9 over other CPPs also helps isolate the role of the Arg sidechain on the translocation without the effect of other sidechains. Therefore, in this work we study computationally the translocation of Arg-9 through a lipid bilayer and show that the translocation mechanism is the same as for the Tat peptide.
- Species Reactivity
- HIV
- Applications
- Antibody assay: Enzyme-linked Immunosorbent Assay; Immunocytochemistry; Functional studies
Product Property
- Purity
- >95% (SDS-PAGE)
- Storage
- Short term: store at 4°C (over 6 months), long term: -20°C or -80°C.
Target
- Alternative Names
- HIV vif; SOR protein; Virion infectivity factor
- Gene ID
- 155459
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "HIV Vif"
Select a product category from the dropdown menu below to view related products.
Please select product type
Intrabody Products
Mouse Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| IAB-B036(G) | Recombinant Anti-HIV Vif Intrabody [+36 GFP] | PCA, Neut, FuncS | scFv-(+36GFP) |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for IAB-B036(A). Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
-1-1.png)
Application: IP, IF, FuncS, FC, Neut, ELISA, IHC
-1.png)
Application: ELISA, FC, Block, SPR
Application: FC, IB, Block, Inhib, FuncS, ELISA, FACS, IP, IF
-1.png)
Application: WB, ELISA
Application: WB, ELISA, FuncS, Inhib, PK, IP, SPR
Application: Neut, ELISA, FuncS
Application: ELISA, IHC, FC, IP, IF, FuncS
Application: ELISA, IHC, FC, IP, IF, Inhib
Application: FC
Application: ELISA
Application: ELISA, WB
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
