Afuco™ Anti-Human HPN ADCC Recombinant Antibody, ADCC Enhanced
CAT#: AFC-350CL
Anti-HPN ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. This is an isolated antibody that binds a hepsin, which provides important therapeutic and diagnostic agents for use in targeting pathological conditions associated with expression and/or activity of the hepsin signaling pathways.
Gene Expression
Normal Tissue
Figure 1 Cerebral cortex
Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Glial cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Neuronal cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/6804/19524_B_7_5.jpg
Normal Tissue
Figure 2 Colon
Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Glandular cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/6804/19524_A_7_3.jpg
Normal Tissue
Figure 3 Liver
Cholangiocytes
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Hepatocytes
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/6804/19524_A_8_4.jpg
Normal Tissue
Figure 4 Kidney
Cells in glomeruli
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Cells in tubules
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/6804/19524_A_8_5.jpg
Normal Tissue
Figure 5 Testis
Cells in seminiferous ducts
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Leydig cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/6804/19524_A_4_6.jpg
RNA Expression
Figure 6 RNA cell line category: Group enriched (EFO-21, Hep G2, T-47d)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000105707-HPN
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Specifications
- Host Species
- Humanized
- Derivation
- Humanized
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Cancer
Product Property
- Purity
- >95%, by SDS-PAGE with Coomassie Brilliant Blue staining
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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See other products for "HPN"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-1314-VHH | Recombinant Anti-Human HPN VHH Single Domain Antibody | ICC, FC, WB, FUNC | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2151z | Mouse Anti-HPN Recombinant Antibody (clone 19A1) | WB, ELISA, IP | Mouse IgG2a, κ |
| PABL-125 | Human Anti-HPN Recombinant Antibody (PABL-125) | WB, ELISA, FuncS | Human IgG |
| HPAB-0223-LSX | Mouse Anti-HPN Recombinant Antibody (clone 25) | ELISA | Mouse IgG |
| HPAB-0224-LSX | Human Anti-HPN Recombinant Antibody (clone mAb55) | ELISA, FC, Inhib | Humanized IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-125 | Human Anti-HPN Recombinant Antibody scFv Fragment (PSBL-125) | WB, ELISA, FuncS | Human scFv |
| HPAB-0223-LSX-S(P) | Mouse Anti-HPN Recombinant Antibody (clone 25); scFv Fragment | ELISA | Mouse scFv |
| HPAB-0224-LSX-S(P) | Human Anti-HPN Recombinant Antibody (clone mAb55); scFv Fragment | ELISA | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-125 | Human Anti-HPN Recombinant Antibody Fab Fragment (PFBL-125) | WB, ELISA, FuncS | Human Fab |
| HPAB-0223-LSX-F(E) | Mouse Anti-HPN Recombinant Antibody (clone 25); Fab Fragment | ELISA | Mouse Fab |
| HPAB-0224-LSX-F(E) | Human Anti-HPN Recombinant Antibody (clone mAb55); Fab Fragment | ELISA | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-029CT | Anti-Human Hepsin Recombinant Antibody (hH35) | ELISA, WB | Humanized antibody |
| TAB-031CT | Human Anti-HPN Recombinant Antibody (TAB-031CT) | WB | Humanized IgG |
| TAB-029CT-S(P) | Anti-Human Hepsin Recombinant Antibody scFv Fragment (hH35) | ELISA, WB | Humanized antibody |
| TAB-031CT-S(P) | Human Anti-HPN Recombinant Antibody; scFv Fragment (TAB-031CT-S(P)) | WB | Humanized scFv |
| TAB-029CT-F(E) | Anti-Human Hepsin Recombinant Antibody Fab Fragment (hH35) | ELISA, WB | Humanized antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-030CT | Anti-Human Hepsin Recombinant Antibody (Mab2.7.35) | ELISA, Inhibition, FC | Chimeric antibody (mouse/human) |
| TAB-030CT-S(P) | Anti-Human Hepsin Recombinant Antibody scFv Fragment (Mab2.7.35) | ELISA, Inhibition, FC | Chimeric antibody (mouse/human) |
| TAB-030CT-F(E) | Anti-Human Hepsin Recombinant Antibody Fab Fragment (Mab2.7.35) | ELISA, Inhibition, FC | Chimeric antibody (mouse/human) |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC349 | Recombinant Anti-HPN Vesicular Antibody, EV Displayed (VS-0425-YC349) | ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3274 | Anti-HPN Immunohistochemistry Kit | IHC |
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