Recombinant Mouse anti-Human ERBB4 Monoclonal antibody (I5.83.9) (CAT#: MOB-0689CT)
Recombinant Mouse monoclonal antibody to Human ERBB4, expressed in Chinese Hamster Ovary cells(CHO).
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Normal Tissue
RNA Expression
Figure 1 Kidney
(Cells in tubules Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12016/35976_A_7_5.jpg
(Cells in tubules Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12016/35976_A_7_5.jpg
Figure 2 Cerebral cortex
(Endothelial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12016/35976_B_8_5.jpg
(Endothelial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12016/35976_B_8_5.jpg
Figure 3 Colon
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12016/35976_A_7_3.jpg
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12016/35976_A_7_3.jpg
Figure 4 Liver
(Hepatocytes Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12016/35976_A_8_4.jpg
(Hepatocytes Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12016/35976_A_8_4.jpg
Figure 5 RNA cell line category: Cell line enhanced (AF22, EFO-21, HEK93, RPTEC TERT1, SCLC-21H, T-47d)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000178568-ERBB4
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000178568-ERBB4
Specifications
- Immunogen
- Extracellular domain of recombinant human ErbB 4
- Host Species
- Mouse
- Specificity
- It is particularly well suited for inhibiting the binding of heregulin (NDF) to ErbB 4. It has no effect on tyrosine kinase activity or internalization of ErbB 4. It immunoprecipitates only the unoccupied receptor.
- Species Reactivity
- Human
- Clone
- I5.83.9
- Applications
- Used for immunoassay techniques such as: Flow Cytometry
- Conjugate
- Biotin
Product Property
- Purity
- Protein A purified
- Format
- Liquid
- Concentration
- 0.2 mg/ml
- Buffer
- Preservative: 0.09% Sodium Azide Constituents: 0.2% BSA, 10mM PBS, pH 7.4
- Storage
- Store at +4°C.
Target
- Alternative Names
- ERBB4; erb-b2 receptor tyrosine kinase 4; HER4; ALS19; p180erbB4; receptor tyrosine-protein kinase erbB-4; proto-oncogene-like protein c-ErbB-4; human epidermal growth factor receptor 4; tyrosine kinase-type cell surface receptor HER4; v-erb-a erythroblastic leukemia viral oncogene homolog 4; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4; avian erythroblastic leukemia viral (v-erb-b2) oncogene homolog 4;
- Gene ID
- 2066
- UniProt ID
- Q15303
- Protein Refseq
- NP_001036064
- Function
- ATP binding; nucleotide binding; protein binding; receptor activity; receptor signaling protein tyrosine kinase activity; transmembrane receptor protein tyrosine kinase activity;
Related Resources
ErbB Signaling Pathway
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IHC Kits & Antibodies
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-470 | Mouse Anti-ERBB4 Recombinant Antibody (PABL-470) | WB, IF, FuncS | Mouse IgG |
| HPAB-0530YY | Human Anti-ERBB4 Recombinant Antibody (HPAB-0530YY) | ELISA | Human IgG1 |
| HPAB-0531YY | Human Anti-ERBB4 Recombinant Antibody (HPAB-0531YY) | ELISA | Human IgG1 |
| HPAB-0532YY | Human Anti-ERBB4 Recombinant Antibody (HPAB-0532YY) | ELISA | Human IgG1 |
| VS3-XY647 | Mouse Anti-ERBB4 Recombinant Antibody (clone 2F7B2) | ELISA, WB, IHC, FC | Mouse IgG1 |
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